Atrial natriuretic peptide regulates regional vascular volume and venous tone in humans

Matthias Schmitt, Andrew J M Broadley, Angus K Nightingale, Nicola Payne, Prasad Gunaruwan, Justin Taylor, Leong Lee, John Cockcroft, Allan D Struthers, Michael P Frenneaux

Research output: Contribution to journalArticlepeer-review

14 Citations (Scopus)


To date, the contribution of basal atrial natriuretic peptide (ANP) levels to resting vascular function in humans is unknown. In the present study we sought to investigate the role of ANP in regulating regional vascular volume and venous tone in healthy subjects.
Original languageEnglish
Pages (from-to)1833-1838
Number of pages6
JournalArteriosclerosis, Thrombosis, and Vascular Biology
Issue number10
Early online date3 Jul 2003
Publication statusPublished - 1 Oct 2003


  • Adult
  • Aged
  • Atrial Natriuretic Factor
  • Blood Volume
  • Compliance
  • Dose-Response Relationship, Drug
  • Female
  • Forearm
  • Humans
  • Infusions, Intravenous
  • Male
  • Middle Aged
  • Peptide Fragments
  • Receptors, Atrial Natriuretic Factor
  • Regional Blood Flow
  • Tetrahydroisoquinolines
  • Vasodilation
  • Veins

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