Bacterial microcompartments moving into a synthetic biological world

Stefanie Frank, Andrew D. Lawrence, Michael B. Prentice, Martin J. Warren

Research output: Contribution to journalArticlepeer-review

79 Citations (Scopus)

Abstract

Bacterial microcompartments are proteinaceous organelles that are found in a broad range of bacteria. They are composed of an outer protein shell that encases a specific metabolic process. Examples include the carboxysome, which houses enzymes associated with carbon fixation, and the propanediol metabolosome, which contains enzymes linked with the catabolism of propanediol to propionic acid. In this article the molecular structure of bacterial microcompartments is examined and the potential to engineer these intriguing organelles for biotechnological applications is explored.

Original languageEnglish
Pages (from-to)273-279
Number of pages7
JournalJournal of Biotechnology
Volume163
Issue number2
DOIs
Publication statusPublished - Jan 2013

Keywords

  • Bacterial microcompartment
  • Carboxysome
  • Metabolism
  • Organelle
  • Propanediol utilisation

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