Baroreflex sensitivity is reduced in depression

Andrew J M Broadley, Michael P Frenneaux, Valentina Moskvina, Chris J H Jones, Ania Korszun

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Depression is independently associated with increased cardiovascular morbidity and mortality, including sudden cardiac death, and this risk is observed even in patients who have been successfully treated for depression. Recent studies have emphasized the importance of impaired baroreceptor sensitivity (BRS) as a predisposing factor for sudden death in patients with manifest cardiac disease. Our objective was to test the hypothesis that BRS is impaired in subjects with depression in remission and with no other cardiac risk factors.
Original languageEnglish
Pages (from-to)648-651
Number of pages4
JournalPsychosomatic Medicine
Issue number4
Publication statusPublished - 2005


  • Adult
  • Baroreflex
  • Depressive Disorder, Major
  • Female
  • Humans
  • Male
  • Myocardial Ischemia
  • Recurrence

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