Barrett's esophagus: progression to adenocarcinoma and markers

Dianchun Fang; Kiron M Das; Weibiao Cao; Usha Malhotra; George Triadafilopoulos; Robert M Najarian; Laura J Hardie; Charles J Lightdale; Ian L P Beales; Valter Nilton Felix; Paul M Schneider; Andrew M Bellizzi

doi:10.1111/j.1749-6632.2011.06053.x

Barrett's esophagus: progression to adenocarcinoma and markers

Dianchun Fang
, Kiron M Das
, Weibiao Cao
, Usha Malhotra
, George Triadafilopoulos
, Robert M Najarian
, Laura J Hardie
, Charles J Lightdale
, Ian L P Beales
, Valter Nilton Felix
, Paul M Schneider
, Andrew M Bellizzi

Research output: Contribution to journal › Article › peer-review

15 Citations (Scopus)

Abstract

The following on progression to adenocarcinoma and markers of Barrett's esophagus includes commentariess on the expression of claudin 4 in Barrett's adenocarcinoma; the role of acid and bile salts; the role of insulin-like growth factor; the value of reactive oxygen species; the importance of abnormal methylation; genetic alterations in stromal cells and genomic changes in the epithelial cells; the value of confocal laser endomicroscopy for the subsurface analysis of the mucosa; indications for statins as adjuvant chemotherapeutic agent; the sequence of molecular events in malignant progression in Barrett's mucosa; and the value of the macroscopic markers and of p53 mutations.

Original language	English
Pages (from-to)	210-29
Number of pages	20
Journal	Annals of the New York Academy of Sciences
Volume	1232
DOIs	https://doi.org/10.1111/j.1749-6632.2011.06053.x
Publication status	Published - Sept 2011

Keywords

Adenocarcinoma
Barrett Esophagus
Disease Progression
Esophageal Neoplasms
Humans
NADPH Oxidase
Reverse Transcriptase Polymerase Chain Reaction
Tumor Markers, Biological

Access to Document

10.1111/j.1749-6632.2011.06053.x

Cite this

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title = "Barrett's esophagus: progression to adenocarcinoma and markers",

abstract = "The following on progression to adenocarcinoma and markers of Barrett's esophagus includes commentariess on the expression of claudin 4 in Barrett's adenocarcinoma; the role of acid and bile salts; the role of insulin-like growth factor; the value of reactive oxygen species; the importance of abnormal methylation; genetic alterations in stromal cells and genomic changes in the epithelial cells; the value of confocal laser endomicroscopy for the subsurface analysis of the mucosa; indications for statins as adjuvant chemotherapeutic agent; the sequence of molecular events in malignant progression in Barrett's mucosa; and the value of the macroscopic markers and of p53 mutations.",

keywords = "Adenocarcinoma, Barrett Esophagus, Disease Progression, Esophageal Neoplasms, Humans, NADPH Oxidase, Reverse Transcriptase Polymerase Chain Reaction, Tumor Markers, Biological",

author = "Dianchun Fang and Das, \{Kiron M\} and Weibiao Cao and Usha Malhotra and George Triadafilopoulos and Najarian, \{Robert M\} and Hardie, \{Laura J\} and Lightdale, \{Charles J\} and Beales, \{Ian L P\} and Felix, \{Valter Nilton\} and Schneider, \{Paul M\} and Bellizzi, \{Andrew M\}",

note = "{\textcopyright} 2011 New York Academy of Sciences.",

year = "2011",

month = sep,

doi = "10.1111/j.1749-6632.2011.06053.x",

language = "English",

volume = "1232",

pages = "210--29",

journal = "Annals of the New York Academy of Sciences",

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publisher = "Wiley",

}

TY - JOUR

T1 - Barrett's esophagus

T2 - progression to adenocarcinoma and markers

AU - Fang, Dianchun

AU - Das, Kiron M

AU - Cao, Weibiao

AU - Malhotra, Usha

AU - Triadafilopoulos, George

AU - Najarian, Robert M

AU - Hardie, Laura J

AU - Lightdale, Charles J

AU - Beales, Ian L P

AU - Felix, Valter Nilton

AU - Schneider, Paul M

AU - Bellizzi, Andrew M

PY - 2011/9

Y1 - 2011/9

N2 - The following on progression to adenocarcinoma and markers of Barrett's esophagus includes commentariess on the expression of claudin 4 in Barrett's adenocarcinoma; the role of acid and bile salts; the role of insulin-like growth factor; the value of reactive oxygen species; the importance of abnormal methylation; genetic alterations in stromal cells and genomic changes in the epithelial cells; the value of confocal laser endomicroscopy for the subsurface analysis of the mucosa; indications for statins as adjuvant chemotherapeutic agent; the sequence of molecular events in malignant progression in Barrett's mucosa; and the value of the macroscopic markers and of p53 mutations.

AB - The following on progression to adenocarcinoma and markers of Barrett's esophagus includes commentariess on the expression of claudin 4 in Barrett's adenocarcinoma; the role of acid and bile salts; the role of insulin-like growth factor; the value of reactive oxygen species; the importance of abnormal methylation; genetic alterations in stromal cells and genomic changes in the epithelial cells; the value of confocal laser endomicroscopy for the subsurface analysis of the mucosa; indications for statins as adjuvant chemotherapeutic agent; the sequence of molecular events in malignant progression in Barrett's mucosa; and the value of the macroscopic markers and of p53 mutations.

KW - Adenocarcinoma

KW - Barrett Esophagus

KW - Disease Progression

KW - Esophageal Neoplasms

KW - Humans

KW - NADPH Oxidase

KW - Reverse Transcriptase Polymerase Chain Reaction

KW - Tumor Markers, Biological

U2 - 10.1111/j.1749-6632.2011.06053.x

DO - 10.1111/j.1749-6632.2011.06053.x

M3 - Article

C2 - 21950815

SN - 0077-8923

VL - 1232

SP - 210

EP - 229

JO - Annals of the New York Academy of Sciences

JF - Annals of the New York Academy of Sciences

ER -