Bifidobacterium bacteraemia is rare with routine probiotics use in preterm infants: A further case report with literature review

Antia Acuna-Gonzalez, Magdalena Kujawska, Mayada Youssif, Thomas Atkinson, Sara Grundy, Alexandra Hutchison, Catherine Tremlett, Paul Clarke, Lindsay J. Hall

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Prophylactic administration of oral probiotics is associated with significant reductions in the morbidity and mortality of necrotising enterocolitis in preterm infants. We document the first case of Bifidobacterium longum subsp. infantis sub-clinical bacteraemia, in an extremely low birth weight preterm infant, since introduction of routine probiotic treatment at the Norfolk and Norwich University Hospital 10 years ago. Whole genome comparisons confirmed the isolated strain likely originated from the probiotic product.
Original languageEnglish
Article number102713
Early online date6 Feb 2023
Publication statusPublished - Apr 2023

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