Bifunctional alkylating agents derived from duocarmycin SA: Potent antitumor activity with altered sequence selectivity

Dale L. Boger; Mark Searcey; Winston C. Tse; Qing Jin

doi:10.1016/S0960-894X(00)00042-1

Bifunctional alkylating agents derived from duocarmycin SA: Potent antitumor activity with altered sequence selectivity

Dale L. Boger, Mark Searcey, Winston C. Tse, Qing Jin

Research output: Contribution to journal › Article › peer-review

11 Citations (Scopus)

Abstract

Original language	English
Pages (from-to)	495-498
Number of pages	4
Journal	Bioorganic & Medicinal Chemistry Letters
Volume	10
Issue number	5
DOIs	https://doi.org/10.1016/S0960-894X(00)00042-1
Publication status	Published - 6 Mar 2000

Keywords

AMIDE
CC-1065
PYRINDAMYCIN-A
STREPTOMYCES SP
BINDING
CATALYSIS
ANALOGS
DNA
SUBUNITS
ANTIBIOTICS

Access to Document

10.1016/S0960-894X(00)00042-1

Cite this

@article{eb83b4d7302d4d6fbd0fa09b3f484a6d,

title = "Bifunctional alkylating agents derived from duocarmycin SA: Potent antitumor activity with altered sequence selectivity",

abstract = "The series of four dimers derived from head to tail coupling of the two enantiomers of the duocarmycin SA alkylation subunit are described. (C) 2000 Elsevier Science Ltd. All rights reserved.",

keywords = "AMIDE, CC-1065, PYRINDAMYCIN-A, STREPTOMYCES SP, BINDING, CATALYSIS, ANALOGS, DNA, SUBUNITS, ANTIBIOTICS",

author = "Boger, {Dale L.} and Mark Searcey and Tse, {Winston C.} and Qing Jin",

year = "2000",

month = mar,

day = "6",

doi = "10.1016/S0960-894X(00)00042-1",

language = "English",

volume = "10",

pages = "495--498",

journal = "Bioorganic & Medicinal Chemistry Letters",

issn = "0960-894X",

publisher = "Elsevier",

number = "5",

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TY - JOUR

T1 - Bifunctional alkylating agents derived from duocarmycin SA: Potent antitumor activity with altered sequence selectivity

AU - Boger, Dale L.

AU - Searcey, Mark

AU - Tse, Winston C.

AU - Jin, Qing

PY - 2000/3/6

Y1 - 2000/3/6

KW - AMIDE

KW - CC-1065

KW - PYRINDAMYCIN-A

KW - STREPTOMYCES SP

KW - BINDING

KW - CATALYSIS

KW - ANALOGS

KW - DNA

KW - SUBUNITS

KW - ANTIBIOTICS

U2 - 10.1016/S0960-894X(00)00042-1

DO - 10.1016/S0960-894X(00)00042-1

M3 - Article

VL - 10

SP - 495

EP - 498

JO - Bioorganic & Medicinal Chemistry Letters

JF - Bioorganic & Medicinal Chemistry Letters

SN - 0960-894X

IS - 5

ER -