Bridging gaps in transposable element research with single-molecule and single-cell technologies

Claudia Kutter; Patric Jern; Alexander Suh

doi:10.1186/s13100-018-0140-5

Bridging gaps in transposable element research with single-molecule and single-cell technologies

Claudia Kutter, Patric Jern, Alexander Suh

School of Biological Sciences

Research output: Contribution to journal › Article › peer-review

5 Citations (Scopus)

Abstract

More than half of the genomic landscape in humans and many other organisms is composed of repetitive DNA, which mostly derives from transposable elements (TEs) and viruses. Recent technological advances permit improved assessment of the repetitive content across genomes and newly developed molecular assays have revealed important roles of TEs and viruses in host genome evolution and organization. To update on our current understanding of TE biology and to promote new interdisciplinary strategies for the TE research community, leading experts gathered for the 2^nd Uppsala Transposon Symposium on October 4-5, 2018 in Uppsala, Sweden. Using cutting-edge single-molecule and single-cell approaches, research on TEs and other repeats has entered a new era in biological and biomedical research.

Original language	English
Article number	140
Journal	Mobile DNA
Volume	9
Issue number	1
DOIs	https://doi.org/10.1186/s13100-018-0140-5
Publication status	Published - 6 Dec 2018

Keywords

Centromeres
Endogenous viruses
Evolution
Long read-sequencing
Repetitive sequence
Satellites
Transposable elements

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10.1186/s13100-018-0140-5Licence: CC BY

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Bridging gaps in transposable element research with single-molecule and single-cell technologies

Abstract

Keywords

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