C15 acetogenins with antistaphylococcal activity from the red alga Laurencia glandulifera

Maria Kladi; Constantinos Vagias; Michael Stavri; M. Mukhlesur Rahman; Simon Gibbons; Vassilios Roussis

doi:10.1016/j.phytol.2007.12.004

C15 acetogenins with antistaphylococcal activity from the red alga Laurencia glandulifera

Maria Kladi, Constantinos Vagias, Michael Stavri, M. Mukhlesur Rahman, Simon Gibbons, Vassilios Roussis

Research output: Contribution to journal › Article › peer-review

35 Citations (Scopus)

Abstract

Five new C15 eight-membered cyclic ethers (1, 3–6) with a characteristic terminal cis ene–yne moiety, along with the previously reported acetylenic chloro diol (2) were isolated from the organic extract of the red alga Laurencia glandulifera, collected at Crete island in South Greece. Full assignment of all 1H and 13C resonances were carried out by extensive analysis of their NMR spectra. All metabolites were tested for their antistaphylococcal activity and the minimum inhibitory concentrations (MICs) of 2–5 were in the range of 8–256 μg/ml.

Original language	English
Pages (from-to)	31-36
Number of pages	6
Journal	Phytochemistry Letters
Volume	1
Issue number	1
Early online date	21 Feb 2008
DOIs	https://doi.org/10.1016/j.phytol.2007.12.004
Publication status	Published - 15 Apr 2008

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10.1016/j.phytol.2007.12.004

https://linkinghub.elsevier.com/retrieve/pii/S1874390007000092

Cite this

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abstract = "Five new C15 eight-membered cyclic ethers (1, 3–6) with a characteristic terminal cis ene–yne moiety, along with the previously reported acetylenic chloro diol (2) were isolated from the organic extract of the red alga Laurencia glandulifera, collected at Crete island in South Greece. Full assignment of all 1H and 13C resonances were carried out by extensive analysis of their NMR spectra. All metabolites were tested for their antistaphylococcal activity and the minimum inhibitory concentrations (MICs) of 2–5 were in the range of 8–256 μg/ml.",

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AU - Kladi, Maria

AU - Vagias, Constantinos

AU - Stavri, Michael

AU - Rahman, M. Mukhlesur

AU - Gibbons, Simon

AU - Roussis, Vassilios

PY - 2008/4/15

Y1 - 2008/4/15

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AB - Five new C15 eight-membered cyclic ethers (1, 3–6) with a characteristic terminal cis ene–yne moiety, along with the previously reported acetylenic chloro diol (2) were isolated from the organic extract of the red alga Laurencia glandulifera, collected at Crete island in South Greece. Full assignment of all 1H and 13C resonances were carried out by extensive analysis of their NMR spectra. All metabolites were tested for their antistaphylococcal activity and the minimum inhibitory concentrations (MICs) of 2–5 were in the range of 8–256 μg/ml.

U2 - 10.1016/j.phytol.2007.12.004

DO - 10.1016/j.phytol.2007.12.004

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JO - Phytochemistry Letters

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