C4-symmetric alkoxyresorcin[4]arene triflates: The use of palladium-catalyzed reactions in the synthesis of axially chiral derivatives with amino- and/or alkoxy-substituents

Philip C. Bulman Page, Terence R. Bygrave, Yohan Chan, Harry Heaney, Vickie McKee

Research output: Contribution to journalArticlepeer-review

7 Citations (Scopus)


The conversion of axially chiral tetraalkoxyresorcin[4]arenes (cyclochiral resorcinarenes) into the related tetrakis(triflates) in high yields is described; this provides an efficient source of chiral materials for use in palladium-catalyzed transformations, including the reductive removal of triflate groups and the synthesis of compounds that are formally derived from 3-aminophenol, providing axially chiral derivatives that are nitrogen-substituted on the upper rim.
Original languageEnglish
Pages (from-to)3016-3025
Number of pages10
JournalEuropean Journal of Organic Chemistry
Issue number16
Publication statusPublished - 2011

Cite this