Can the irradiated brain be salvaged by oligodendrocyte precursor transplantation?

Marie C. Harrisingh; Charles ffrench-Constant

doi:10.1016/j.stem.2015.01.010

Can the irradiated brain be salvaged by oligodendrocyte precursor transplantation?

Marie C. Harrisingh, Charles ffrench-Constant

Norwich Medical School

Research output: Contribution to journal › Short survey › peer-review

5 Citations (Scopus)

Abstract

Radiotherapy is a mainstay of brain cancer treatment, but it causes significant complications. In this issue of Cell Stem Cell, Piao et al. (2015) derive oligodendrocyte precursors from human embryonic stem cells and show that engrafted cells replenish depleted precursor numbers, generate new myelin, and reverse behavioral defects in irradiated rats.

Original language	English
Pages (from-to)	113-114
Number of pages	2
Journal	Cell Stem Cell
Volume	16
Issue number	2
DOIs	https://doi.org/10.1016/j.stem.2015.01.010
Publication status	Published - 5 Feb 2015

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Cite this

@article{d858ca691d424cc7bc4138e1b79267f1,

title = "Can the irradiated brain be salvaged by oligodendrocyte precursor transplantation?",

abstract = "Radiotherapy is a mainstay of brain cancer treatment, but it causes significant complications. In this issue of Cell Stem Cell, Piao et al. (2015) derive oligodendrocyte precursors from human embryonic stem cells and show that engrafted cells replenish depleted precursor numbers, generate new myelin, and reverse behavioral defects in irradiated rats.",

author = "Harrisingh, {Marie C.} and Charles ffrench-Constant",

year = "2015",

month = feb,

day = "5",

doi = "10.1016/j.stem.2015.01.010",

language = "English",

volume = "16",

pages = "113--114",

journal = "Cell Stem Cell",

issn = "1934-5909",