Ca2+ signals in plant immunity

Philipp Köster, Thomas A. DeFalco, Cyril Zipfel

Research output: Contribution to journalReview articlepeer-review

84 Citations (Scopus)
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Calcium ions function as a key second messenger ion in eukaryotes. Spatially and temporally defined cytoplasmic Ca2+ signals are shaped through the concerted activity of ion channels, exchangers, and pumps in response to diverse stimuli; these signals are then decoded through the activity of Ca2+-binding sensor proteins. In plants, Ca2+ signaling is central to both pattern- and effector-triggered immunity, with the generation of characteristic cytoplasmic Ca2+ elevations in response to potential pathogens being common to both. However, despite their importance, and a long history of scientific interest, the transport proteins that shape Ca2+ signals and their integration remain poorly characterized. Here, we discuss recent work that has both shed light on and deepened the mysteries of Ca2+ signaling in plant immunity.

Original languageEnglish
Article numbere110741
JournalEMBO Journal
Issue number12
Early online date13 May 2022
Publication statusPublished - 14 Jun 2022
Externally publishedYes


  • calcium
  • channel
  • ETI
  • immunity
  • PTI

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