Catch-up growth following intra-uterine growth-restriction programmes an insulin-resistant phenotype in adipose tissue

L M Berends; D S Fernandez-Twinn; M S Martin-Gronert; R L Cripps; S E Ozanne

doi:10.1038/ijo.2012.196

Catch-up growth following intra-uterine growth-restriction programmes an insulin-resistant phenotype in adipose tissue

L M Berends, D S Fernandez-Twinn, M S Martin-Gronert, R L Cripps, S E Ozanne

Norwich Medical School

Research output: Contribution to journal › Article › peer-review

89 Citations (Scopus)

Abstract

It is now widely accepted that the early-life nutritional environment is important in determining susceptibility to metabolic diseases. In particular, intra-uterine growth restriction followed by accelerated postnatal growth is associated with an increased risk of obesity, type-2 diabetes and other features of the metabolic syndrome. The mechanisms underlying these observations are not fully understood.

Original language	English
Pages (from-to)	1051-1057
Number of pages	7
Journal	International Journal of Obesity
Volume	37
Issue number	8
DOIs	https://doi.org/10.1038/ijo.2012.196
Publication status	Published - Aug 2013

Keywords

developmental programming
maternal under-nutrition
catch-up growth
adipose tissue
insulin resistance
type-2 diabetes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1038/ijo.2012.196

Cite this

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