Caudiquinol: A meroterpenoid with an intact C20 geranylgeranyl chain isolated from Garcinia caudiculata

Maya Valmiki; Stephen Ping Teo; Pedro Ernesto de Resende; Simon Gibbons; A. Ganesan

doi:10.3390/molecules29153613

Caudiquinol: A meroterpenoid with an intact C20 geranylgeranyl chain isolated from Garcinia caudiculata

Maya Valmiki, Stephen Ping Teo, Pedro Ernesto de Resende, Simon Gibbons, A. Ganesan

School of Chemistry, Pharmacy and Pharmacology

Research output: Contribution to journal › Article › peer-review

Abstract

The tropical Garcinia genus of flowering plants is a prolific producer of aromatic natural products including polyphenols, flavonoids, and xanthones. In this study, we report the first phytochemical investigation of Garcinia caudiculata Ridl. from the island of Borneo. Fractionation, purification, and structure elucidation by MS and NMR resulted in the discovery of two meroterpenoids. One was a benzofuranone lactone previously isolated from Iryanthera grandis and Rhus chinensis, and the second was a new hydroquinone methyl ester that we named caudiquinol. Both natural products are rare examples of plant meroterpenoids with an intact geranylgeranyl chain.

Original language	English
Article number	3613
Journal	Molecules
Volume	29
Issue number	15
Early online date	31 Jul 2024
DOIs	https://doi.org/10.3390/molecules29153613
Publication status	Published - Aug 2024

Keywords

Garcinia species
hydroquinones
meroterpenoids
natural products

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molecules-29-03613Final published version, 761 KBLicence: CC BY

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title = "Caudiquinol: A meroterpenoid with an intact C20 geranylgeranyl chain isolated from Garcinia caudiculata",

abstract = "The tropical Garcinia genus of flowering plants is a prolific producer of aromatic natural products including polyphenols, flavonoids, and xanthones. In this study, we report the first phytochemical investigation of Garcinia caudiculata Ridl. from the island of Borneo. Fractionation, purification, and structure elucidation by MS and NMR resulted in the discovery of two meroterpenoids. One was a benzofuranone lactone previously isolated from Iryanthera grandis and Rhus chinensis, and the second was a new hydroquinone methyl ester that we named caudiquinol. Both natural products are rare examples of plant meroterpenoids with an intact geranylgeranyl chain.",

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note = "Data Availability Statement: The data are contained within this article and the Supplementary Materials. Funding Information: This research received no external funding. We thank the University of East Anglia for awarding a studentship to M.V.",

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AU - Gibbons, Simon

AU - Ganesan, A.

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N2 - The tropical Garcinia genus of flowering plants is a prolific producer of aromatic natural products including polyphenols, flavonoids, and xanthones. In this study, we report the first phytochemical investigation of Garcinia caudiculata Ridl. from the island of Borneo. Fractionation, purification, and structure elucidation by MS and NMR resulted in the discovery of two meroterpenoids. One was a benzofuranone lactone previously isolated from Iryanthera grandis and Rhus chinensis, and the second was a new hydroquinone methyl ester that we named caudiquinol. Both natural products are rare examples of plant meroterpenoids with an intact geranylgeranyl chain.

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Caudiquinol: A meroterpenoid with an intact C20 geranylgeranyl chain isolated from Garcinia caudiculata

Abstract

Keywords

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