Cellular uptake of a fluorescent vanadyl sulfonylcalix[4]arene

Carl Redshaw, Mark R. J. Elsegood, Joseph A. Wright, Hugo Baillie-Johnson, Takehiko Yamato, Stephen De Giovanni, Anja Mueller

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24 Citations (Scopus)


Vanadyl bearing calix[4]arene ligands have undergone evaluation against several cell lines, and show varying degrees of toxicity. For vanadyl complexed to a sulfonylcalix[4]arene, monitoring of the strong blue fluorescence revealed slow uptake kinetics. The complex is exclusively found in the cytoplasm of the cells and uptake is not due to active endocytotic mechanisms.
Original languageEnglish
Pages (from-to)1129-1131
Number of pages3
JournalChemical Communications
Issue number8
Publication statusPublished - 28 Jan 2012

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