Cellular uptake studies of two hexanuclear, carboxylate bridged, zinc ring structures using fluorescence microscopy

Carl Redshaw; Mark R. J. Elsegood; Josef W. A. Frese; Shane Ashby; Yimin Chao; Anja Mueller

doi:10.1039/c2cc32060f

Cellular uptake studies of two hexanuclear, carboxylate bridged, zinc ring structures using fluorescence microscopy

Carl Redshaw
, Mark R. J. Elsegood
, Josef W. A. Frese
, Shane Ashby
, Yimin Chao
, Anja Mueller

Pharmacology and Biological Chemistry

Research output: Contribution to journal › Article › peer-review

19 Citations (Scopus)

Abstract

Two hexanuclear zinc complexes have been structurally characterized, and evaluation against several cells showed selective toxicity. Cellular uptake revealed a non-specific process, resulting in accumulation within the cell cytoplasm.

Original language	English
Pages (from-to)	6627-6629
Number of pages	3
Journal	Chemical Communications
Volume	48
Issue number	53
DOIs	https://doi.org/10.1039/c2cc32060f
Publication status	Published - 1 May 2012

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10.1039/c2cc32060f

Cite this

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title = "Cellular uptake studies of two hexanuclear, carboxylate bridged, zinc ring structures using fluorescence microscopy",

abstract = "Two hexanuclear zinc complexes have been structurally characterized, and evaluation against several cells showed selective toxicity. Cellular uptake revealed a non-specific process, resulting in accumulation within the cell cytoplasm.",

author = "Carl Redshaw and Elsegood, \{Mark R. J.\} and Frese, \{Josef W. A.\} and Shane Ashby and Yimin Chao and Anja Mueller",

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AU - Redshaw, Carl

AU - Elsegood, Mark R. J.

AU - Frese, Josef W. A.

AU - Ashby, Shane

AU - Chao, Yimin

AU - Mueller, Anja

PY - 2012/5/1

Y1 - 2012/5/1

N2 - Two hexanuclear zinc complexes have been structurally characterized, and evaluation against several cells showed selective toxicity. Cellular uptake revealed a non-specific process, resulting in accumulation within the cell cytoplasm.

AB - Two hexanuclear zinc complexes have been structurally characterized, and evaluation against several cells showed selective toxicity. Cellular uptake revealed a non-specific process, resulting in accumulation within the cell cytoplasm.

U2 - 10.1039/c2cc32060f

DO - 10.1039/c2cc32060f

M3 - Article

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VL - 48

SP - 6627

EP - 6629

JO - Chemical Communications

JF - Chemical Communications

IS - 53

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