Change in serum lipids after acute coronary syndromes: secondary analysis of SPACE ROCKET study data and a comparative literature review

Julian H Barth; Beryl M Jackson; Amanda J Farrin; Maria Efthymiou; Gillian Worthy; Joanne Copeland; Kristian M Bailey; Simon P R Romaine; Anthony J Balmforth; Terry McCormack; Andrew Whitehead; Marcus D Flather; Jane Nixon; Alistair S Hall; SPACE ROCKET Trial Group

doi:10.1373/clinchem.2010.145631

Change in serum lipids after acute coronary syndromes: secondary analysis of SPACE ROCKET study data and a comparative literature review

Julian H Barth, Beryl M Jackson, Amanda J Farrin, Maria Efthymiou, Gillian Worthy, Joanne Copeland, Kristian M Bailey, Simon P R Romaine, Anthony J Balmforth, Terry McCormack, Andrew Whitehead, Marcus D Flather, Jane Nixon, Alistair S Hall, SPACE ROCKET Trial Group

Research output: Contribution to journal › Article › peer-review

24 Citations (Scopus)

Abstract

It has long been an accepted belief that serum cholesterol significantly falls after myocardial infarction and that a return to pre-event levels takes approximately 3 months. The magnitude and clinical significance of this fall has recently been challenged.

Original language	English
Pages (from-to)	1592-8
Number of pages	7
Journal	Clinical Chemistry
Volume	56
Issue number	10
DOIs	https://doi.org/10.1373/clinchem.2010.145631
Publication status	Published - Oct 2010

Keywords

Cholesterol
Fluorobenzenes
Humans
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Lipids
Multicenter Studies as Topic
Myocardial Infarction
Pyrimidines
Randomized Controlled Trials as Topic
Simvastatin
Sulfonamides
Triglycerides

Access to Document

10.1373/clinchem.2010.145631

Cite this

Barth, J. H., Jackson, B. M., Farrin, A. J., Efthymiou, M., Worthy, G., Copeland, J., Bailey, K. M., Romaine, S. P. R., Balmforth, A. J., McCormack, T., Whitehead, A., Flather, M. D., Nixon, J., Hall, A. S., & SPACE ROCKET Trial Group (2010). Change in serum lipids after acute coronary syndromes: secondary analysis of SPACE ROCKET study data and a comparative literature review. Clinical Chemistry, 56(10), 1592-8. https://doi.org/10.1373/clinchem.2010.145631

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title = "Change in serum lipids after acute coronary syndromes: secondary analysis of SPACE ROCKET study data and a comparative literature review",

abstract = "It has long been an accepted belief that serum cholesterol significantly falls after myocardial infarction and that a return to pre-event levels takes approximately 3 months. The magnitude and clinical significance of this fall has recently been challenged.",

keywords = "Cholesterol, Fluorobenzenes, Humans, Hydroxymethylglutaryl-CoA Reductase Inhibitors, Lipids, Multicenter Studies as Topic, Myocardial Infarction, Pyrimidines, Randomized Controlled Trials as Topic, Simvastatin, Sulfonamides, Triglycerides",

author = "Barth, {Julian H} and Jackson, {Beryl M} and Farrin, {Amanda J} and Maria Efthymiou and Gillian Worthy and Joanne Copeland and Bailey, {Kristian M} and Romaine, {Simon P R} and Balmforth, {Anthony J} and Terry McCormack and Andrew Whitehead and Flather, {Marcus D} and Jane Nixon and Hall, {Alistair S} and {SPACE ROCKET Trial Group}",

year = "2010",

month = oct,

doi = "10.1373/clinchem.2010.145631",

language = "English",

volume = "56",

pages = "1592--8",

journal = "Clinical Chemistry",

issn = "0009-9147",

publisher = "American Association for Clinical Chemistry Inc.",

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Barth, JH, Jackson, BM, Farrin, AJ, Efthymiou, M, Worthy, G, Copeland, J, Bailey, KM, Romaine, SPR, Balmforth, AJ, McCormack, T, Whitehead, A, Flather, MD, Nixon, J, Hall, AS & SPACE ROCKET Trial Group 2010, 'Change in serum lipids after acute coronary syndromes: secondary analysis of SPACE ROCKET study data and a comparative literature review', Clinical Chemistry, vol. 56, no. 10, pp. 1592-8. https://doi.org/10.1373/clinchem.2010.145631

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T2 - secondary analysis of SPACE ROCKET study data and a comparative literature review

AU - Barth, Julian H

AU - Jackson, Beryl M

AU - Farrin, Amanda J

AU - Efthymiou, Maria

AU - Worthy, Gillian

AU - Copeland, Joanne

AU - Bailey, Kristian M

AU - Romaine, Simon P R

AU - Balmforth, Anthony J

AU - McCormack, Terry

AU - Whitehead, Andrew

AU - Flather, Marcus D

AU - Nixon, Jane

AU - Hall, Alistair S

AU - SPACE ROCKET Trial Group

PY - 2010/10

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N2 - It has long been an accepted belief that serum cholesterol significantly falls after myocardial infarction and that a return to pre-event levels takes approximately 3 months. The magnitude and clinical significance of this fall has recently been challenged.

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KW - Cholesterol

KW - Fluorobenzenes

KW - Humans

KW - Hydroxymethylglutaryl-CoA Reductase Inhibitors

KW - Lipids

KW - Multicenter Studies as Topic

KW - Myocardial Infarction

KW - Pyrimidines

KW - Randomized Controlled Trials as Topic

KW - Simvastatin

KW - Sulfonamides

KW - Triglycerides

U2 - 10.1373/clinchem.2010.145631

DO - 10.1373/clinchem.2010.145631

M3 - Article

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VL - 56

SP - 1592

EP - 1598

JO - Clinical Chemistry

JF - Clinical Chemistry

SN - 0009-9147

IS - 10

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