Chronic oral ascorbic acid therapy worsens skeletal muscle metabolism in patients with chronic heart failure

Angus K Nightingale; Jenifer G Crilley; Nicholas C Pegge; Ernie A Boehm; Catherine Mumford; Doris J Taylor; Peter Styles; Kieran Clarke; Michael P Frenneaux

doi:10.1016/j.ejheart.2006.06.006

Chronic oral ascorbic acid therapy worsens skeletal muscle metabolism in patients with chronic heart failure

Angus K Nightingale, Jenifer G Crilley, Nicholas C Pegge, Ernie A Boehm, Catherine Mumford, Doris J Taylor, Peter Styles, Kieran Clarke, Michael P Frenneaux

Research output: Contribution to journal › Article › peer-review

23 Citations (Scopus)

Abstract

Chronic heart failure (CHF) is associated with abnormalities of skeletal muscle metabolism. This may be due to impaired oxygen delivery as a result of endothelial dysfunction.

Original language	English
Pages (from-to)	287-291
Number of pages	5
Journal	European Journal of Heart Failure
Volume	9
Issue number	3
DOIs	https://doi.org/10.1016/j.ejheart.2006.06.006
Publication status	Published - Mar 2007

Keywords

Adenosine Triphosphate
Aged
Ascorbic Acid
Chronic Disease
Double-Blind Method
Endothelium, Vascular
Female
Great Britain
Heart Failure
Humans
Magnetic Resonance Spectroscopy
Male
Middle Aged
Muscle, Skeletal
Phosphocreatine

Access to Document

10.1016/j.ejheart.2006.06.006

Cite this

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title = "Chronic oral ascorbic acid therapy worsens skeletal muscle metabolism in patients with chronic heart failure",

abstract = "Chronic heart failure (CHF) is associated with abnormalities of skeletal muscle metabolism. This may be due to impaired oxygen delivery as a result of endothelial dysfunction.",

keywords = "Adenosine Triphosphate, Aged, Ascorbic Acid, Chronic Disease, Double-Blind Method, Endothelium, Vascular, Female, Great Britain, Heart Failure, Humans, Magnetic Resonance Spectroscopy, Male, Middle Aged, Muscle, Skeletal, Phosphocreatine",

author = "Nightingale, {Angus K} and Crilley, {Jenifer G} and Pegge, {Nicholas C} and Boehm, {Ernie A} and Catherine Mumford and Taylor, {Doris J} and Peter Styles and Kieran Clarke and Frenneaux, {Michael P}",

year = "2007",

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doi = "10.1016/j.ejheart.2006.06.006",

language = "English",

volume = "9",

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journal = "European Journal of Heart Failure",

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AU - Nightingale, Angus K

AU - Crilley, Jenifer G

AU - Pegge, Nicholas C

AU - Boehm, Ernie A

AU - Mumford, Catherine

AU - Taylor, Doris J

AU - Styles, Peter

AU - Clarke, Kieran

AU - Frenneaux, Michael P

PY - 2007/3

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AB - Chronic heart failure (CHF) is associated with abnormalities of skeletal muscle metabolism. This may be due to impaired oxygen delivery as a result of endothelial dysfunction.

KW - Adenosine Triphosphate

KW - Aged

KW - Ascorbic Acid

KW - Chronic Disease

KW - Double-Blind Method

KW - Endothelium, Vascular

KW - Female

KW - Great Britain

KW - Heart Failure

KW - Humans

KW - Magnetic Resonance Spectroscopy

KW - Male

KW - Middle Aged

KW - Muscle, Skeletal

KW - Phosphocreatine

U2 - 10.1016/j.ejheart.2006.06.006

DO - 10.1016/j.ejheart.2006.06.006

M3 - Article

C2 - 17023203

SN - 1388-9842

VL - 9

SP - 287

EP - 291

JO - European Journal of Heart Failure

JF - European Journal of Heart Failure

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ER -