Chronic rhinosinusitis and mood disturbance

Sally Erskine, Julian Beezhold, Carl Philpott

Research output: Contribution to conferencePosterpeer-review


Objectives: This study is part of the Chronic Rhinosinusitis Epidemiology Study (CRES). The overarching aim is to determine factors that influence the onset and severity of chronic rhinosinusitis (CRS).The aim of this analysis is to determine the number of patients consulting with their family physician about anxiety or depression among those with CRS and controls. Methods: CRES is a mixed methods study of patients with CRS including qualitative interviews and study-specific questionnaires. This analysis considers only the questionnaires. These included comprehensive questions about demographic and socioeconomic factors and past medical history as well as SNOT-22 (nasal symptom score) and SF-36 (quality of life tool). Questionnaires were distributed to patients with CRS attending general ENT and rhinology clinics within the National Health Service and private sector and to a control population across many centers in the United Kingdom from 2004 to 2013. Results: A total of 1519 participants, including 57 with AFRS (allergic fungal rhinosinusitis), 659 CRSwNP (with nasal polyps), 577 CRSsNP (without nasal polyps), and 236 controls. Self-reported consultation with family physician for depression was 9 out of 57 (15.8%), 132 out of 659 (20.0%), 142 out of 577 (24.6%), and 36 out of 226 (15.9%), respectively. P < .02 for differences between participant subgroups. For anxiety: AFRS 10 out of 57 (17.5%), CRSwNP 105 out of 659 (15.9%), CRSsNP 130 out of 577 (22.5%), controls 39 out of 236 (16.5%), P = .04 between groups. Conclusions: There are differences in rates of consulting with family physicians for depression and anxiety disease between those with different types of CRS and controls; those with CRS without polyps were most likely to have consulted. This may influence management strategies for patients with different nasal pathologies.
Original languageEnglish
Number of pages1
Publication statusPublished - Sep 2014
Event24th European Congress of Psychiatry (EPA 2016) - Madrid, Spain
Duration: 12 Mar 201615 Mar 2016


Conference24th European Congress of Psychiatry (EPA 2016)


  • Chronic rhinosinusitis
  • Depression
  • Anxiety Disorders

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