Ciprofibrate therapy improves endothelial function and reduces postprandial lipemia and oxidative stress in type 2 diabetes mellitus

Marc Evans, Richard A. Anderson, John Graham, Gethin R. Ellis, Keith Morris, Stephen Davies, Simon K. Jackson, Malcolm J. Lewis, Michael P. Frenneaux, Alan Rees

Research output: Contribution to journalArticle

207 Citations (Scopus)

Abstract

Exaggerated postprandial lipemia (PPL) is a factor in atherogenesis, involving endothelial dysfunction and enhanced oxidative stress. We examined the effect of ciprofibrate therapy on these parameters in type 2 diabetes mellitus.
Original languageEnglish
Pages (from-to)1773-1779
Number of pages7
JournalCirculation
Volume101
Issue number15
DOIs
Publication statusPublished - 18 Apr 2000

Keywords

  • Adult
  • Analysis of Variance
  • Area Under Curve
  • Cholesterol, HDL
  • Clofibric Acid
  • Diabetes Mellitus, Type 2
  • Double-Blind Method
  • Endothelium, Vascular
  • Female
  • Fibric Acids
  • Humans
  • Hypolipidemic Agents
  • Lipids
  • Male
  • Middle Aged
  • Oxidative Stress
  • Postprandial Period
  • Triglycerides

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