Coherent Electron Transport across a 3 nm Bioelelectronic Junction made of Multi-heme Proteins

Futera Zdenek, Ichiro Ide, Ben Kayser, Kavita Garg, Xiuyun Jiang, Jessica H. van Wonderen, Julea N. Butt, Hisao Ishii, Israel Pecht, Mordechai Sheves, David Cahen, Jochen Blumberger

Research output: Contribution to journalArticle

Abstract

Multi-heme cytochromes (MHCs) are fascinating proteins used by bacterial
organisms to shuttle electrons within and between their cells. When placed in solid state electronic junctions, MHCs support temperature-independent currents over several nanometers that are three orders of magnitude higher compared to other redox proteins. To gain molecular-level insight into their astonishingly high conductivities, we combine experimental photoemission spectroscopy with DFT+Σ current-voltage calculations on a representative MHC-gold junction. We find that conduction across the dry, 3 nm-long protein occurs via off-resonant coherent tunneling, mediated by a large number of protein valence-band orbitals that are strongly delocalized over heme and protein residues. This picture is profoundly different from the electron hopping
mechanism induced electrochemically or photochemically under aqueous conditions. Our results imply that the current output in solid state junctions can be even further increased in resonance, e.g. by applying a gate voltage, thus allowing a quantum jump for next-generation bionanoelectronic devices.
Original languageEnglish
Pages (from-to)9766–9774
Number of pages9
JournalThe Journal of Physical Chemistry Letters
Volume11
Issue number22
Early online date3 Nov 2020
Publication statusPublished - 19 Nov 2020

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