Colonic CD8 and gamma delta T-cell infiltration with epithelial damage in children with autism

Raoul I. Furlano, Andrew Anthony, Richard Day, Angela Brown, Louise McGarvey, Michael A. Thomson, Susan E. Davies, Mark Berelowitz, Alastair Forbes, Andrew J. Wakefield, John A. Walker-Smith, Simon H. Murch

Research output: Contribution to journalArticle

162 Citations (Scopus)

Abstract

We have reported colitis with ileal lymphoid nodular hyperplasia (LNH) in children with regressive autism. The aims of this study were to characterize this lesion and determine whether LNH is specific for autism.
Original languageEnglish
Pages (from-to)366-372
Number of pages7
JournalJournal of Pediatrics
Volume138
Issue number3
DOIs
Publication statusPublished - Mar 2001

Keywords

  • Adolescent
  • Autistic Disorder
  • CD8-Positive T-Lymphocytes
  • Case-Control Studies
  • Child
  • Child, Preschool
  • Female
  • Humans
  • Infant
  • Inflammatory Bowel Diseases
  • Intestinal Mucosa
  • Lymphatic Diseases
  • Male
  • T-Lymphocytes

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