Comparative effects of dietary flavanols on antioxidant defences and their response to oxidant-induced stress on Caco2 cells

Ildefonso Rodriguez Ramiro; María Angeles Martín; Sonia Ramos; Laura Bravo; Luis Goya

doi:10.1007/s00394-010-0139-2

Comparative effects of dietary flavanols on antioxidant defences and their response to oxidant-induced stress on Caco2 cells

Ildefonso Rodriguez Ramiro, María Angeles Martín, Sonia Ramos, Laura Bravo, Luis Goya

Norwich Medical School

Research output: Contribution to journal › Article › peer-review

74 Citations (Scopus)

Abstract

Flavanols are an important fraction of our diet both for their antioxidant capacity and because they are constituents of greatly accepted foodstuffs such as tea, wine and cocoa. In addition to their antioxidant activity by directly scavenging intracellular reactive oxygen species (ROS), flavanols have been recently shown to enhance protective enzymes. The objective was to evaluate the antioxidant response of colon-derived Caco2 cells to dietary flavanols.

Original language	English
Pages (from-to)	313-322
Number of pages	10
Journal	European Journal of Nutrition
Volume	50
Issue number	5
DOIs	https://doi.org/10.1007/s00394-010-0139-2
Publication status	Published - Aug 2011

Keywords

Antioxidants
Glutathione
Humans
Caspase 3
Caco-2 Cells
Catechin
Reactive Oxygen Species
Cell Survival
Biflavonoids
Proanthocyanidins
Oxidative Stress
Glutathione Peroxidase
Diet
Epicatechin
Epicatechin gallate
Epigallocatechin-3-gallate
Flavonoids

Access to Document

10.1007/s00394-010-0139-2

Cite this

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title = "Comparative effects of dietary flavanols on antioxidant defences and their response to oxidant-induced stress on Caco2 cells",

abstract = "Flavanols are an important fraction of our diet both for their antioxidant capacity and because they are constituents of greatly accepted foodstuffs such as tea, wine and cocoa. In addition to their antioxidant activity by directly scavenging intracellular reactive oxygen species (ROS), flavanols have been recently shown to enhance protective enzymes. The objective was to evaluate the antioxidant response of colon-derived Caco2 cells to dietary flavanols.",

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author = "{Rodriguez Ramiro}, Ildefonso and Mart{\'i}n, {Mar{\'i}a Angeles} and Sonia Ramos and Laura Bravo and Luis Goya",

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language = "English",

volume = "50",

pages = "313--322",

journal = "European Journal of Nutrition",

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TY - JOUR

T1 - Comparative effects of dietary flavanols on antioxidant defences and their response to oxidant-induced stress on Caco2 cells

AU - Rodriguez Ramiro, Ildefonso

AU - Martín, María Angeles

AU - Ramos, Sonia

AU - Bravo, Laura

AU - Goya, Luis

PY - 2011/8

Y1 - 2011/8

N2 - Flavanols are an important fraction of our diet both for their antioxidant capacity and because they are constituents of greatly accepted foodstuffs such as tea, wine and cocoa. In addition to their antioxidant activity by directly scavenging intracellular reactive oxygen species (ROS), flavanols have been recently shown to enhance protective enzymes. The objective was to evaluate the antioxidant response of colon-derived Caco2 cells to dietary flavanols.

AB - Flavanols are an important fraction of our diet both for their antioxidant capacity and because they are constituents of greatly accepted foodstuffs such as tea, wine and cocoa. In addition to their antioxidant activity by directly scavenging intracellular reactive oxygen species (ROS), flavanols have been recently shown to enhance protective enzymes. The objective was to evaluate the antioxidant response of colon-derived Caco2 cells to dietary flavanols.

KW - Antioxidants

KW - Glutathione

KW - Humans

KW - Caspase 3

KW - Caco-2 Cells

KW - Catechin

KW - Reactive Oxygen Species

KW - Cell Survival

KW - Biflavonoids

KW - Proanthocyanidins

KW - Oxidative Stress

KW - Glutathione Peroxidase

KW - Diet

KW - Epicatechin

KW - Epicatechin gallate

KW - Epigallocatechin-3-gallate

KW - Flavonoids

U2 - 10.1007/s00394-010-0139-2

DO - 10.1007/s00394-010-0139-2

M3 - Article

C2 - 21046126

VL - 50

SP - 313

EP - 322

JO - European Journal of Nutrition

JF - European Journal of Nutrition

SN - 1436-6207

IS - 5

ER -