Comparative effects of dietary flavanols on antioxidant defences and their response to oxidant-induced stress on Caco2 cells

Ildefonso Rodriguez Ramiro, María Angeles Martín, Sonia Ramos, Laura Bravo, Luis Goya

Research output: Contribution to journalArticlepeer-review

69 Citations (Scopus)


Flavanols are an important fraction of our diet both for their antioxidant capacity and because they are constituents of greatly accepted foodstuffs such as tea, wine and cocoa. In addition to their antioxidant activity by directly scavenging intracellular reactive oxygen species (ROS), flavanols have been recently shown to enhance protective enzymes. The objective was to evaluate the antioxidant response of colon-derived Caco2 cells to dietary flavanols.
Original languageEnglish
Pages (from-to)313-322
Number of pages10
JournalEuropean Journal of Nutrition
Issue number5
Publication statusPublished - Aug 2011


  • Antioxidants
  • Glutathione
  • Humans
  • Caspase 3
  • Caco-2 Cells
  • Catechin
  • Reactive Oxygen Species
  • Cell Survival
  • Biflavonoids
  • Proanthocyanidins
  • Oxidative Stress
  • Glutathione Peroxidase
  • Diet
  • Epicatechin
  • Epicatechin gallate
  • Epigallocatechin-3-gallate
  • Flavonoids

Cite this