Comparative genomic analysis of human infective Trypanosoma cruzi lineages with the bat-restricted subspecies T. cruzi marinkellei

Oscar Franzén, Carlos Talavera-López, Stephen Ochaya, Claire Butler, Louisa A Messenger, Michael D Lewis, Martin S Llewellyn, Cornelis J Marinkelle, Kevin Tyler, Michael A Miles, Björn Andersson

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42 Citations (Scopus)

Abstract

Trypanosoma cruzi marinkellei is a bat-associated parasite of the subgenus Schizotrypanum and it is regarded as a T. cruzi subspecies. Here we report a draft genome sequence of T. c. marinkellei and comparison with T. c. cruzi. Our aims were to identify unique sequences and genomic features, which may relate to their distinct niches.
Original languageEnglish
Article number531
JournalBMC Genomics
Volume13
DOIs
Publication statusPublished - 5 Oct 2012

Keywords

  • Genetic Linkage
  • Trypanosoma cruzi
  • DNA Copy Number Variations
  • Animals
  • Chiroptera
  • Trypanosoma
  • Humans
  • DNA, Protozoan
  • Acetyltransferases
  • Computational Biology
  • Chagas Disease
  • Retroelements

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