Comparative genomic analysis of human infective Trypanosoma cruzi lineages with the bat-restricted subspecies T. cruzi marinkellei

Oscar Franzén; Carlos Talavera-López; Stephen Ochaya; Claire Butler; Louisa A Messenger; Michael D Lewis; Martin S Llewellyn; Cornelis J Marinkelle; Kevin Tyler; Michael A Miles; Björn Andersson

doi:10.1186/1471-2164-13-531

Comparative genomic analysis of human infective Trypanosoma cruzi lineages with the bat-restricted subspecies T. cruzi marinkellei

Oscar Franzén
, Carlos Talavera-López
, Stephen Ochaya
, Claire Butler
, Louisa A Messenger
, Michael D Lewis
, Martin S Llewellyn
, Cornelis J Marinkelle
, Kevin Tyler
, Michael A Miles
, Björn Andersson

Research output: Contribution to journal › Article › peer-review

46 Citations (Scopus)

Abstract

Trypanosoma cruzi marinkellei is a bat-associated parasite of the subgenus Schizotrypanum and it is regarded as a T. cruzi subspecies. Here we report a draft genome sequence of T. c. marinkellei and comparison with T. c. cruzi. Our aims were to identify unique sequences and genomic features, which may relate to their distinct niches.

Original language	English
Article number	531
Journal	BMC Genomics
Volume	13
DOIs	https://doi.org/10.1186/1471-2164-13-531
Publication status	Published - 5 Oct 2012

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Genetic Linkage
Trypanosoma cruzi
DNA Copy Number Variations
Animals
Chiroptera
Trypanosoma
Humans
DNA, Protozoan
Acetyltransferases
Computational Biology
Chagas Disease
Retroelements

Access to Document

10.1186/1471-2164-13-531Licence: CC BY

http://www.biomedcentral.com/1471-2164/13/531Licence: CC BY

Cite this

Franzén, O., Talavera-López, C., Ochaya, S., Butler, C., Messenger, L. A., Lewis, M. D., Llewellyn, M. S., Marinkelle, C. J., Tyler, K., Miles, M. A., & Andersson, B. (2012). Comparative genomic analysis of human infective Trypanosoma cruzi lineages with the bat-restricted subspecies T. cruzi marinkellei. BMC Genomics, 13, Article 531. https://doi.org/10.1186/1471-2164-13-531

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abstract = "Trypanosoma cruzi marinkellei is a bat-associated parasite of the subgenus Schizotrypanum and it is regarded as a T. cruzi subspecies. Here we report a draft genome sequence of T. c. marinkellei and comparison with T. c. cruzi. Our aims were to identify unique sequences and genomic features, which may relate to their distinct niches. ",

keywords = "Genetic Linkage, Trypanosoma cruzi, DNA Copy Number Variations, Animals, Chiroptera, Trypanosoma, Humans, DNA, Protozoan, Acetyltransferases, Computational Biology, Chagas Disease, Retroelements",

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AU - Franzén, Oscar

AU - Talavera-López, Carlos

AU - Ochaya, Stephen

AU - Butler, Claire

AU - Messenger, Louisa A

AU - Lewis, Michael D

AU - Llewellyn, Martin S

AU - Marinkelle, Cornelis J

AU - Tyler, Kevin

AU - Miles, Michael A

AU - Andersson, Björn

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KW - Genetic Linkage

KW - Trypanosoma cruzi

KW - DNA Copy Number Variations

KW - Animals

KW - Chiroptera

KW - Trypanosoma

KW - Humans

KW - DNA, Protozoan

KW - Acetyltransferases

KW - Computational Biology

KW - Chagas Disease

KW - Retroelements

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JO - BMC Genomics

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