Comparative in vitro activity of sulfametrole/trimethoprim and sulfamethoxazole/trimethoprim and other agents against multiresistant Gram-negative bacteria

David M Livermore, Shazad Mushtaq, Marina Warner, Neil Woodford

Research output: Contribution to journalArticlepeer-review

26 Citations (Scopus)


Sulfamethoxazole/trimethoprim is standard therapy for infections caused by opportunist non-fermenters except Pseudomonas aeruginosa and Acinetobacter. Sulfametrol(e)/trimethoprim is an alternative to sulfamethoxazole/trimethoprim available in some EU countries, with possible pharmacological advantages. We compared their activities against (i) non-fermenters, (ii) multiresistant Enterobacteriaceae and (iii) reference strains with sul1 and sul2.
Original languageEnglish
Pages (from-to)1050-1056
Number of pages7
JournalJournal of Antimicrobial Chemotherapy
Issue number4
Early online date19 Nov 2013
Publication statusPublished - 2014

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