Comparative in vitro activity of sulfametrole/trimethoprim and sulfamethoxazole/trimethoprim and other agents against multiresistant Gram-negative bacteria

David M Livermore; Shazad Mushtaq; Marina Warner; Neil Woodford

doi:10.1093/jac/dkt455

Comparative in vitro activity of sulfametrole/trimethoprim and sulfamethoxazole/trimethoprim and other agents against multiresistant Gram-negative bacteria

David M Livermore, Shazad Mushtaq, Marina Warner, Neil Woodford

Research output: Contribution to journal › Article › peer-review

26 Citations (Scopus)

Abstract

Sulfamethoxazole/trimethoprim is standard therapy for infections caused by opportunist non-fermenters except Pseudomonas aeruginosa and Acinetobacter. Sulfametrol(e)/trimethoprim is an alternative to sulfamethoxazole/trimethoprim available in some EU countries, with possible pharmacological advantages. We compared their activities against (i) non-fermenters, (ii) multiresistant Enterobacteriaceae and (iii) reference strains with sul1 and sul2.

Original language	English
Pages (from-to)	1050-1056
Number of pages	7
Journal	Journal of Antimicrobial Chemotherapy
Volume	69
Issue number	4
Early online date	19 Nov 2013
DOIs	https://doi.org/10.1093/jac/dkt455
Publication status	Published - 2014

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10.1093/jac/dkt455

Cite this

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abstract = "Sulfamethoxazole/trimethoprim is standard therapy for infections caused by opportunist non-fermenters except Pseudomonas aeruginosa and Acinetobacter. Sulfametrol(e)/trimethoprim is an alternative to sulfamethoxazole/trimethoprim available in some EU countries, with possible pharmacological advantages. We compared their activities against (i) non-fermenters, (ii) multiresistant Enterobacteriaceae and (iii) reference strains with sul1 and sul2.",

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AU - Warner, Marina

AU - Woodford, Neil

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AB - Sulfamethoxazole/trimethoprim is standard therapy for infections caused by opportunist non-fermenters except Pseudomonas aeruginosa and Acinetobacter. Sulfametrol(e)/trimethoprim is an alternative to sulfamethoxazole/trimethoprim available in some EU countries, with possible pharmacological advantages. We compared their activities against (i) non-fermenters, (ii) multiresistant Enterobacteriaceae and (iii) reference strains with sul1 and sul2.

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DO - 10.1093/jac/dkt455

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