Comparative in vitro activity of sulfametrole/trimethoprim and sulfamethoxazole/trimethoprim and other agents against multiresistant Gram-negative bacteria

David M Livermore; Shazad Mushtaq; Marina Warner; Neil Woodford

doi:10.1093/jac/dkt455

Comparative in vitro activity of sulfametrole/trimethoprim and sulfamethoxazole/trimethoprim and other agents against multiresistant Gram-negative bacteria

David M Livermore
, Shazad Mushtaq
, Marina Warner
, Neil Woodford

Research output: Contribution to journal › Article › peer-review

28 Citations (Scopus)

Abstract

Sulfamethoxazole/trimethoprim is standard therapy for infections caused by opportunist non-fermenters except Pseudomonas aeruginosa and Acinetobacter. Sulfametrol(e)/trimethoprim is an alternative to sulfamethoxazole/trimethoprim available in some EU countries, with possible pharmacological advantages. We compared their activities against (i) non-fermenters, (ii) multiresistant Enterobacteriaceae and (iii) reference strains with sul1 and sul2.

Original language	English
Pages (from-to)	1050-1056
Number of pages	7
Journal	Journal of Antimicrobial Chemotherapy
Volume	69
Issue number	4
Early online date	19 Nov 2013
DOIs	https://doi.org/10.1093/jac/dkt455
Publication status	Published - 2014

Access to Document

10.1093/jac/dkt455

Cite this

@article{3d62ba3dcdaa4ad3b71b7907244588cd,

title = "Comparative in vitro activity of sulfametrole/trimethoprim and sulfamethoxazole/trimethoprim and other agents against multiresistant Gram-negative bacteria",

abstract = "Sulfamethoxazole/trimethoprim is standard therapy for infections caused by opportunist non-fermenters except Pseudomonas aeruginosa and Acinetobacter. Sulfametrol(e)/trimethoprim is an alternative to sulfamethoxazole/trimethoprim available in some EU countries, with possible pharmacological advantages. We compared their activities against (i) non-fermenters, (ii) multiresistant Enterobacteriaceae and (iii) reference strains with sul1 and sul2.",

author = "Livermore, \{David M\} and Shazad Mushtaq and Marina Warner and Neil Woodford",

year = "2014",

doi = "10.1093/jac/dkt455",

language = "English",

volume = "69",

pages = "1050--1056",

journal = "Journal of Antimicrobial Chemotherapy",

issn = "0305-7453",

publisher = "Oxford University Press",

number = "4",

}

TY - JOUR

T1 - Comparative in vitro activity of sulfametrole/trimethoprim and sulfamethoxazole/trimethoprim and other agents against multiresistant Gram-negative bacteria

AU - Livermore, David M

AU - Mushtaq, Shazad

AU - Warner, Marina

AU - Woodford, Neil

PY - 2014

Y1 - 2014

N2 - Sulfamethoxazole/trimethoprim is standard therapy for infections caused by opportunist non-fermenters except Pseudomonas aeruginosa and Acinetobacter. Sulfametrol(e)/trimethoprim is an alternative to sulfamethoxazole/trimethoprim available in some EU countries, with possible pharmacological advantages. We compared their activities against (i) non-fermenters, (ii) multiresistant Enterobacteriaceae and (iii) reference strains with sul1 and sul2.

AB - Sulfamethoxazole/trimethoprim is standard therapy for infections caused by opportunist non-fermenters except Pseudomonas aeruginosa and Acinetobacter. Sulfametrol(e)/trimethoprim is an alternative to sulfamethoxazole/trimethoprim available in some EU countries, with possible pharmacological advantages. We compared their activities against (i) non-fermenters, (ii) multiresistant Enterobacteriaceae and (iii) reference strains with sul1 and sul2.

U2 - 10.1093/jac/dkt455

DO - 10.1093/jac/dkt455

M3 - Article

C2 - 24257317

SN - 0305-7453

VL - 69

SP - 1050

EP - 1056

JO - Journal of Antimicrobial Chemotherapy

JF - Journal of Antimicrobial Chemotherapy

IS - 4

ER -