Comparison of Image Acquisition Techniques in Four-Dimensional Flow Cardiovascular MR on 3 Tesla in Volunteers and Tetralogy of Fallot Patients

Jun-Mei Zhang, Ju Le Tan, Jos J. M. Westenberg, Liang Zhong, Ru San Tan, Shuo Zhang, Rob Van Der Geest, Pankaj Garg, Bao Ru Leong, Jennifer Bryant, Tarinee Tangcharoen, Xiaodan Zhao

Research output: Contribution to conferencePaperpeer-review

7 Citations (Scopus)

Abstract

Four-dimensional phase-contrast (PC) velocity-encoded flow magnetic resonance imaging (4D flow MRI) is a potentially valuable tool for studying cardiovascular hemodynamics for disease monitoring and/or treatment planning. In this study we compared the performance of two 4D flow MRI pulse sequences - echo-planar imaging (EPI) and segmented gradient-echo (turbo-field-echo or TFE on vendor's platform) - on a clinical 3T system in 6 human subjects including 3 patients with Tetralogy of Fallot (TOF). For aortic flow rate, the coefficients of variation (COV) between 2D and 4D EPI were 7.0% and 7.7% for controls and patients respectively. The corresponding COV between 2D and 4D TFE were 19.0% and 18.3% for controls and patients respectively. The COV between 4D TFE and 4D EPI were larger than 18.7% in kinetic energy analysis. 4D EPI demonstrated acceptable accuracy of intra-cardiac flow quantification, which was also shown in the ex-vivo phantom measurements.
Original languageEnglish
Pages1115-1118
Number of pages4
DOIs
Publication statusPublished - 29 Oct 2018
Event2018 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) - Honolulu, HI
Duration: 18 Jul 201821 Jul 2018

Conference

Conference2018 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)
Period18/07/1821/07/18

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