Complete Versus culprit-Lesion only PRimary PCI Trial (CVLPRIT): a multicentre trial testing management strategies when multivessel disease is detected at the time of primary PCI: rationale and design

Damian J Kelly, Gerald P McCann, Daniel Blackman, Nicholas P Curzen, Miles Dalby, John P Greenwood, Kathryn Fairbrother, Lorraine Shipley, Andrew Kelion, Simon Heatherington, Jamal N Khan, Sheraz Nazir, Albert Alahmar, Marcus Flather, Howard Swanton, Peter Schofield, Mark Gunning, Roger Hall, Anthony H Gershlick

Research output: Contribution to journalArticlepeer-review

38 Citations (Scopus)

Abstract

Primary percutaneous coronary intervention (PPCI) is the preferred strategy for acute ST-segment elevation myocardial infarction (STEMI), with evidence of improved clinical outcomes compared to fibrinolytic therapy. However, there is no consensus on how best to manage multivessel coronary disease detected at the time of PPCI, with little robust data on best management of angiographically significant stenoses detected in non-infarct-related (N-IRA) coronary arteries. CVLPRIT will determine the optimal management of N-IRA lesions detected during PPCI.
Original languageEnglish
Pages (from-to)1190-8
Number of pages9
JournalEurointervention
Volume8
Issue number10
DOIs
Publication statusPublished - 22 Feb 2013

Keywords

  • Prospective Studies
  • Endpoint Determination
  • Humans
  • Percutaneous Coronary Intervention
  • Research Design
  • Coronary Artery Disease

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