Computed tomographic pulmonary angiography vs ventilation-perfusion lung scanning in patients with suspected pulmonary embolism: a randomized controlled trial

David R Anderson, Susan R Kahn, Marc A Rodger, Michael J Kovacs, Tim Morris, Andrew Hirsch, Eddy Lang, Ian Stiell, George Kovacs, Jon Dreyer, Carol Dennie, Yannick Cartier, David Barnes, Erica Burton, Susan Pleasance, Chris Skedgel, Keith O'Rouke, Philip S Wells

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Abstract

Ventilation-perfusion (V(dot)Q(dot) lung scanning and computed tomographic pulmonary angiography (CTPA) are widely used imaging procedures for the evaluation of patients with suspected pulmonary embolism. Ventilation-perfusion scanning has been largely replaced by CTPA in many centers despite limited comparative formal evaluations and concerns about CTPA's low sensitivity (ie, chance of missing clinically important pulmonary embuli).
Original languageEnglish
Pages (from-to)2743-2753
Number of pages11
JournalJAMA
Volume298
Issue number23
DOIs
Publication statusPublished - 19 Dec 2007

Keywords

  • Adult
  • Aged
  • Angiography
  • Female
  • Humans
  • Male
  • Middle Aged
  • Pulmonary Embolism
  • Radionuclide Imaging
  • Single-Blind Method
  • Tomography, X-Ray Computed
  • Ventilation-Perfusion Ratio

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