Computed tomographic pulmonary angiography vs ventilation-perfusion lung scanning in patients with suspected pulmonary embolism: a randomized controlled trial

David R. Anderson; Susan R. Kahn; Marc A. Rodger; Michael J. Kovacs; Tim Morris; Andrew Hirsch; Eddy Lang; Ian Stiell; George Kovacs; Jon Dreyer; Carol Dennie; Yannick Cartier; David Barnes; Erica Burton; Susan Pleasance; Chris Skedgel; Keith O'Rouke; Philip S. Wells

doi:10.1001/jama.298.23.2743

Computed tomographic pulmonary angiography vs ventilation-perfusion lung scanning in patients with suspected pulmonary embolism: a randomized controlled trial

David R. Anderson, Susan R. Kahn, Marc A. Rodger, Michael J. Kovacs, Tim Morris, Andrew Hirsch, Eddy Lang, Ian Stiell, George Kovacs, Jon Dreyer, Carol Dennie, Yannick Cartier, David Barnes, Erica Burton, Susan Pleasance, Chris Skedgel, Keith O'Rouke, Philip S. Wells

Research output: Contribution to journal › Article › peer-review

491 Citations (Scopus)

Abstract

Ventilation-perfusion (V(dot)Q(dot) lung scanning and computed tomographic pulmonary angiography (CTPA) are widely used imaging procedures for the evaluation of patients with suspected pulmonary embolism. Ventilation-perfusion scanning has been largely replaced by CTPA in many centers despite limited comparative formal evaluations and concerns about CTPA's low sensitivity (ie, chance of missing clinically important pulmonary embuli).

Original language	English
Pages (from-to)	2743-2753
Number of pages	11
Journal	JAMA
Volume	298
Issue number	23
DOIs	https://doi.org/10.1001/jama.298.23.2743
Publication status	Published - 19 Dec 2007

Keywords

Adult
Aged
Angiography
Female
Humans
Male
Middle Aged
Pulmonary Embolism
Radionuclide Imaging
Single-Blind Method
Tomography, X-Ray Computed
Ventilation-Perfusion Ratio

Access to Document

10.1001/jama.298.23.2743

Cite this

Anderson, D. R., Kahn, S. R., Rodger, M. A., Kovacs, M. J., Morris, T., Hirsch, A., Lang, E., Stiell, I., Kovacs, G., Dreyer, J., Dennie, C., Cartier, Y., Barnes, D., Burton, E., Pleasance, S., Skedgel, C., O'Rouke, K., & Wells, P. S. (2007). Computed tomographic pulmonary angiography vs ventilation-perfusion lung scanning in patients with suspected pulmonary embolism: a randomized controlled trial. JAMA, 298(23), 2743-2753. https://doi.org/10.1001/jama.298.23.2743

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title = "Computed tomographic pulmonary angiography vs ventilation-perfusion lung scanning in patients with suspected pulmonary embolism: a randomized controlled trial",

abstract = "Ventilation-perfusion (V(dot)Q(dot) lung scanning and computed tomographic pulmonary angiography (CTPA) are widely used imaging procedures for the evaluation of patients with suspected pulmonary embolism. Ventilation-perfusion scanning has been largely replaced by CTPA in many centers despite limited comparative formal evaluations and concerns about CTPA's low sensitivity (ie, chance of missing clinically important pulmonary embuli).",

keywords = "Adult, Aged, Angiography, Female, Humans, Male, Middle Aged, Pulmonary Embolism, Radionuclide Imaging, Single-Blind Method, Tomography, X-Ray Computed, Ventilation-Perfusion Ratio",

author = "Anderson, {David R.} and Kahn, {Susan R.} and Rodger, {Marc A.} and Kovacs, {Michael J.} and Tim Morris and Andrew Hirsch and Eddy Lang and Ian Stiell and George Kovacs and Jon Dreyer and Carol Dennie and Yannick Cartier and David Barnes and Erica Burton and Susan Pleasance and Chris Skedgel and Keith O'Rouke and Wells, {Philip S.}",

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Anderson, DR, Kahn, SR, Rodger, MA, Kovacs, MJ, Morris, T, Hirsch, A, Lang, E, Stiell, I, Kovacs, G, Dreyer, J, Dennie, C, Cartier, Y, Barnes, D, Burton, E, Pleasance, S, Skedgel, C, O'Rouke, K & Wells, PS 2007, 'Computed tomographic pulmonary angiography vs ventilation-perfusion lung scanning in patients with suspected pulmonary embolism: a randomized controlled trial', JAMA, vol. 298, no. 23, pp. 2743-2753. https://doi.org/10.1001/jama.298.23.2743

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T1 - Computed tomographic pulmonary angiography vs ventilation-perfusion lung scanning in patients with suspected pulmonary embolism: a randomized controlled trial

AU - Anderson, David R.

AU - Kahn, Susan R.

AU - Rodger, Marc A.

AU - Kovacs, Michael J.

AU - Morris, Tim

AU - Hirsch, Andrew

AU - Lang, Eddy

AU - Stiell, Ian

AU - Kovacs, George

AU - Dreyer, Jon

AU - Dennie, Carol

AU - Cartier, Yannick

AU - Barnes, David

AU - Burton, Erica

AU - Pleasance, Susan

AU - Skedgel, Chris

AU - O'Rouke, Keith

AU - Wells, Philip S.

PY - 2007/12/19

Y1 - 2007/12/19

N2 - Ventilation-perfusion (V(dot)Q(dot) lung scanning and computed tomographic pulmonary angiography (CTPA) are widely used imaging procedures for the evaluation of patients with suspected pulmonary embolism. Ventilation-perfusion scanning has been largely replaced by CTPA in many centers despite limited comparative formal evaluations and concerns about CTPA's low sensitivity (ie, chance of missing clinically important pulmonary embuli).

AB - Ventilation-perfusion (V(dot)Q(dot) lung scanning and computed tomographic pulmonary angiography (CTPA) are widely used imaging procedures for the evaluation of patients with suspected pulmonary embolism. Ventilation-perfusion scanning has been largely replaced by CTPA in many centers despite limited comparative formal evaluations and concerns about CTPA's low sensitivity (ie, chance of missing clinically important pulmonary embuli).

KW - Adult

KW - Aged

KW - Angiography

KW - Female

KW - Humans

KW - Male

KW - Middle Aged

KW - Pulmonary Embolism

KW - Radionuclide Imaging

KW - Single-Blind Method

KW - Tomography, X-Ray Computed

KW - Ventilation-Perfusion Ratio

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