Concerted expansion and contraction of immune receptor gene repertoires in plant genomes

Bruno Pok Man Ngou, Robert Heal, Michele Wyler, Marc W. Schmid, Jonathan D. G. Jones

Research output: Contribution to journalArticlepeer-review

36 Citations (Scopus)
6 Downloads (Pure)


Recent reports suggest that cell-surface and intracellular immune receptors function synergistically to activate robust defence against pathogens, but whether they co-evolve is unclear. Here we determined the numbers of cell-surface and intracellular immune receptors in 350 species. Surprisingly, the number of receptor genes that are predicted to encode cell-surface and intracellular immune receptors is strongly correlated. We suggest this is consistent with mutual potentiation of immunity initiated by cell-surface and intracellular receptors being reflected in the concerted co-evolution of the size of their repertoires across plant species.
Original languageEnglish
Pages (from-to)1146-1152
Number of pages7
JournalNature Plants
Issue number10
Publication statusPublished - 14 Oct 2022

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