Concerted expansion and contraction of immune receptor gene repertoires in plant genomes

Bruno Pok Man Ngou; Robert Heal; Michele Wyler; Marc W. Schmid; Jonathan D. G. Jones

doi:10.1038/s41477-022-01260-5

Concerted expansion and contraction of immune receptor gene repertoires in plant genomes

Bruno Pok Man Ngou
, Robert Heal
, Michele Wyler
, Marc W. Schmid
, Jonathan D. G. Jones

Research output: Contribution to journal › Article › peer-review

100 Citations (Scopus)

18 Downloads (Pure)

Abstract

Recent reports suggest that cell-surface and intracellular immune receptors function synergistically to activate robust defence against pathogens, but whether they co-evolve is unclear. Here we determined the numbers of cell-surface and intracellular immune receptors in 350 species. Surprisingly, the number of receptor genes that are predicted to encode cell-surface and intracellular immune receptors is strongly correlated. We suggest this is consistent with mutual potentiation of immunity initiated by cell-surface and intracellular receptors being reflected in the concerted co-evolution of the size of their repertoires across plant species.

Original language	English
Pages (from-to)	1146-1152
Number of pages	7
Journal	Nature Plants
Volume	8
Issue number	10
DOIs	https://doi.org/10.1038/s41477-022-01260-5
Publication status	Published - 14 Oct 2022

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abstract = "Recent reports suggest that cell-surface and intracellular immune receptors function synergistically to activate robust defence against pathogens, but whether they co-evolve is unclear. Here we determined the numbers of cell-surface and intracellular immune receptors in 350 species. Surprisingly, the number of receptor genes that are predicted to encode cell-surface and intracellular immune receptors is strongly correlated. We suggest this is consistent with mutual potentiation of immunity initiated by cell-surface and intracellular receptors being reflected in the concerted co-evolution of the size of their repertoires across plant species.",

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note = "Funding Information: We thank S. Fairhead, J. Rhodes, D. Weigel, A.-L. Laine, M. Moscou, Y. Tanaka and Y. Kadota for discussions and suggestions. R.H. and J.D.G.J. are supported by the Gatsby Foundation. B.P.M.N. was supported by the Norwich Research Park Biosciences Doctoral Training Partnership from the Biotechnology and Biological Sciences Research Council (BBSRC) (grant agreement BB/M011216/1).",

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AU - Ngou, Bruno Pok Man

AU - Heal, Robert

AU - Wyler, Michele

AU - Schmid, Marc W.

AU - Jones, Jonathan D. G.

N1 - Funding Information: We thank S. Fairhead, J. Rhodes, D. Weigel, A.-L. Laine, M. Moscou, Y. Tanaka and Y. Kadota for discussions and suggestions. R.H. and J.D.G.J. are supported by the Gatsby Foundation. B.P.M.N. was supported by the Norwich Research Park Biosciences Doctoral Training Partnership from the Biotechnology and Biological Sciences Research Council (BBSRC) (grant agreement BB/M011216/1).

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N2 - Recent reports suggest that cell-surface and intracellular immune receptors function synergistically to activate robust defence against pathogens, but whether they co-evolve is unclear. Here we determined the numbers of cell-surface and intracellular immune receptors in 350 species. Surprisingly, the number of receptor genes that are predicted to encode cell-surface and intracellular immune receptors is strongly correlated. We suggest this is consistent with mutual potentiation of immunity initiated by cell-surface and intracellular receptors being reflected in the concerted co-evolution of the size of their repertoires across plant species.

AB - Recent reports suggest that cell-surface and intracellular immune receptors function synergistically to activate robust defence against pathogens, but whether they co-evolve is unclear. Here we determined the numbers of cell-surface and intracellular immune receptors in 350 species. Surprisingly, the number of receptor genes that are predicted to encode cell-surface and intracellular immune receptors is strongly correlated. We suggest this is consistent with mutual potentiation of immunity initiated by cell-surface and intracellular receptors being reflected in the concerted co-evolution of the size of their repertoires across plant species.

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DO - 10.1038/s41477-022-01260-5

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JO - Nature Plants

JF - Nature Plants

IS - 10

ER -

Concerted expansion and contraction of immune receptor gene repertoires in plant genomes

Abstract

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