Corey-Chaykovsky reaction of chiral sulfinyl imines: A convenient procedure for the formation of chiral aziridines

Daniel Morton; David Pearson; Robert A. Field; Robert A. Stockman

doi:10.1055/s-2003-42028

Corey-Chaykovsky reaction of chiral sulfinyl imines: A convenient procedure for the formation of chiral aziridines

Daniel Morton, David Pearson, Robert A. Field, Robert A. Stockman

Research output: Contribution to journal › Article › peer-review

53 Citations (Scopus)

Abstract

The reaction of dimethylsulfonium methylide with a range of aromatic, heterocyclic and aliphatic tert-butylsulfinyl imines is presented. Aziridines were formed in 63-84% yield and 77-95% diastereomeric excess.

Original language	English
Pages (from-to)	1985-1988
Number of pages	4
Journal	Synlett
Issue number	13
Early online date	8 Oct 2003
DOIs	https://doi.org/10.1055/s-2003-42028
Publication status	Published - 2003

Keywords

Aziridine
Corey-chaykovsky
Imine
Sulfinyl imine
Ylide

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10.1055/s-2003-42028

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@article{b0bfbe28ac494c75a341c8a513ed3d72,

title = "Corey-Chaykovsky reaction of chiral sulfinyl imines: A convenient procedure for the formation of chiral aziridines",

abstract = "The reaction of dimethylsulfonium methylide with a range of aromatic, heterocyclic and aliphatic tert-butylsulfinyl imines is presented. Aziridines were formed in 63-84% yield and 77-95% diastereomeric excess.",

keywords = "Aziridine, Corey-chaykovsky, Imine, Sulfinyl imine, Ylide",

author = "Daniel Morton and David Pearson and Field, {Robert A.} and Stockman, {Robert A.}",

year = "2003",

doi = "10.1055/s-2003-42028",

language = "English",

pages = "1985--1988",

journal = "Synlett",

issn = "0936-5214",

publisher = "Georg Thieme Verlag",

number = "13",

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TY - JOUR

T1 - Corey-Chaykovsky reaction of chiral sulfinyl imines: A convenient procedure for the formation of chiral aziridines

AU - Morton, Daniel

AU - Pearson, David

AU - Field, Robert A.

AU - Stockman, Robert A.

PY - 2003

Y1 - 2003

N2 - The reaction of dimethylsulfonium methylide with a range of aromatic, heterocyclic and aliphatic tert-butylsulfinyl imines is presented. Aziridines were formed in 63-84% yield and 77-95% diastereomeric excess.

AB - The reaction of dimethylsulfonium methylide with a range of aromatic, heterocyclic and aliphatic tert-butylsulfinyl imines is presented. Aziridines were formed in 63-84% yield and 77-95% diastereomeric excess.

KW - Aziridine

KW - Corey-chaykovsky

KW - Imine

KW - Sulfinyl imine

KW - Ylide

UR - http://www.scopus.com/inward/record.url?scp=0242383439&partnerID=8YFLogxK

U2 - 10.1055/s-2003-42028

DO - 10.1055/s-2003-42028

M3 - Article

AN - SCOPUS:0242383439

SP - 1985

EP - 1988

JO - Synlett

JF - Synlett

SN - 0936-5214

IS - 13

ER -

Corey-Chaykovsky reaction of chiral sulfinyl imines: A convenient procedure for the formation of chiral aziridines

Abstract

Keywords

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