Coronary artery bypass surgery with or without mitral valve annuloplasty in moderate functional ischemic mitral regurgitation: final results of the Randomized Ischemic Mitral Evaluation (RIME) trial

K M John Chan; Prakash P Punjabi; Marcus Flather; Riccardo Wage; Karen Symmonds; Isabelle Roussin; Shelley Rahman-Haley; Dudley J Pennell; Philip J Kilner; Gilles D Dreyfus; John R Pepper; RIME Investigators

doi:10.1161/CIRCULATIONAHA.112.143818

Coronary artery bypass surgery with or without mitral valve annuloplasty in moderate functional ischemic mitral regurgitation: final results of the Randomized Ischemic Mitral Evaluation (RIME) trial

K M John Chan
, Prakash P Punjabi
, Marcus Flather
, Riccardo Wage
, Karen Symmonds
, Isabelle Roussin
, Shelley Rahman-Haley
, Dudley J Pennell
, Philip J Kilner
, Gilles D Dreyfus
, John R Pepper
, RIME Investigators

Research output: Contribution to journal › Article › peer-review

315 Citations (Scopus)

Abstract

The role of mitral valve repair (MVR) during coronary artery bypass grafting (CABG) in patients with moderate ischemic mitral regurgitation (MR) is uncertain. We conducted a randomized, controlled trial to determine whether repairing the mitral valve during CABG may improve functional capacity and left ventricular reverse remodeling compared with CABG alone.

Original language	English
Pages (from-to)	2502-2510
Number of pages	9
Journal	Circulation
Volume	126
Issue number	21
DOIs	https://doi.org/10.1161/CIRCULATIONAHA.112.143818
Publication status	Published - 20 Nov 2012

Keywords

Humans
Myocardial Ischemia
Aged
Single-Blind Method
Aged, 80 and over
Coronary Artery Bypass
Treatment Outcome
Follow-Up Studies
Middle Aged
Mitral Valve Annuloplasty
Female
Male
Mitral Valve Insufficiency
Coronary disease
Mitral valve regurgitation
surgery

Access to Document

10.1161/CIRCULATIONAHA.112.143818

Cite this

Chan, K. M. J., Punjabi, P. P., Flather, M., Wage, R., Symmonds, K., Roussin, I., Rahman-Haley, S., Pennell, D. J., Kilner, P. J., Dreyfus, G. D., Pepper, J. R., & RIME Investigators (2012). Coronary artery bypass surgery with or without mitral valve annuloplasty in moderate functional ischemic mitral regurgitation: final results of the Randomized Ischemic Mitral Evaluation (RIME) trial. Circulation, 126(21), 2502-2510. https://doi.org/10.1161/CIRCULATIONAHA.112.143818

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title = "Coronary artery bypass surgery with or without mitral valve annuloplasty in moderate functional ischemic mitral regurgitation: final results of the Randomized Ischemic Mitral Evaluation (RIME) trial",

abstract = "The role of mitral valve repair (MVR) during coronary artery bypass grafting (CABG) in patients with moderate ischemic mitral regurgitation (MR) is uncertain. We conducted a randomized, controlled trial to determine whether repairing the mitral valve during CABG may improve functional capacity and left ventricular reverse remodeling compared with CABG alone.",

keywords = "Humans, Myocardial Ischemia, Aged, Single-Blind Method, Aged, 80 and over, Coronary Artery Bypass, Treatment Outcome, Follow-Up Studies, Middle Aged, Mitral Valve Annuloplasty, Female, Male, Mitral Valve Insufficiency, Coronary disease, Mitral valve regurgitation, surgery",

author = "Chan, \{K M John\} and Punjabi, \{Prakash P\} and Marcus Flather and Riccardo Wage and Karen Symmonds and Isabelle Roussin and Shelley Rahman-Haley and Pennell, \{Dudley J\} and Kilner, \{Philip J\} and Dreyfus, \{Gilles D\} and Pepper, \{John R\} and \{RIME Investigators\}",

year = "2012",

month = nov,

day = "20",

doi = "10.1161/CIRCULATIONAHA.112.143818",

language = "English",

volume = "126",

pages = "2502--2510",

journal = "Circulation",

publisher = "Lippincott Williams and Wilkins",

number = "21",

}

Chan, KMJ, Punjabi, PP, Flather, M, Wage, R, Symmonds, K, Roussin, I, Rahman-Haley, S, Pennell, DJ, Kilner, PJ, Dreyfus, GD, Pepper, JR & RIME Investigators 2012, 'Coronary artery bypass surgery with or without mitral valve annuloplasty in moderate functional ischemic mitral regurgitation: final results of the Randomized Ischemic Mitral Evaluation (RIME) trial', Circulation, vol. 126, no. 21, pp. 2502-2510. https://doi.org/10.1161/CIRCULATIONAHA.112.143818

Coronary artery bypass surgery with or without mitral valve annuloplasty in moderate functional ischemic mitral regurgitation: final results of the Randomized Ischemic Mitral Evaluation (RIME) trial. / Chan, K M John; Punjabi, Prakash P; Flather, Marcus et al.
In: Circulation, Vol. 126, No. 21, 20.11.2012, p. 2502-2510.

Research output: Contribution to journal › Article › peer-review

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T1 - Coronary artery bypass surgery with or without mitral valve annuloplasty in moderate functional ischemic mitral regurgitation

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KW - Treatment Outcome

KW - Follow-Up Studies

KW - Middle Aged

KW - Mitral Valve Annuloplasty

KW - Female

KW - Male

KW - Mitral Valve Insufficiency

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