Cowpea mosaic virus unmodified empty viruslike particles loaded with metal and metal oxide

Alaa A. A. Aljabali; Frank Sainsbury; George P. Lomonossoff; David J. Evans

doi:10.1002/smll.200902135

Cowpea mosaic virus unmodified empty viruslike particles loaded with metal and metal oxide

Alaa A. A. Aljabali, Frank Sainsbury, George P. Lomonossoff, David J. Evans

School of Biological Sciences

Research output: Contribution to journal › Article › peer-review

72 Citations (Scopus)

Abstract

Empty (devoid of RNA) viruslike particles (eVLPs) of Cowpea mosaic virus can now be obtained readily. CPMV can encapsulate, within the protein capsid, cobalt or iron oxide by environmentally benign processes. The external surface also remains amenable to chemical modification. The development of eVLPs for targeted delivery of therapeutic agents is now a reality.

Original language	English
Pages (from-to)	818-821
Number of pages	4
Journal	Small
Volume	6
Issue number	7
Early online date	8 Mar 2010
DOIs	https://doi.org/10.1002/smll.200902135
Publication status	Published - 9 Apr 2010

Keywords

encapsulation
mineralization
nanoparticles
viruses

Access to Document

10.1002/smll.200902135

http://doi.wiley.com/10.1002/smll.200902135

Cite this

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title = "Cowpea mosaic virus unmodified empty viruslike particles loaded with metal and metal oxide",

abstract = "Empty (devoid of RNA) viruslike particles (eVLPs) of Cowpea mosaic virus can now be obtained readily. CPMV can encapsulate, within the protein capsid, cobalt or iron oxide by environmentally benign processes. The external surface also remains amenable to chemical modification. The development of eVLPs for targeted delivery of therapeutic agents is now a reality.",

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AU - Aljabali, Alaa A. A.

AU - Sainsbury, Frank

AU - Lomonossoff, George P.

AU - Evans, David J.

PY - 2010/4/9

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AB - Empty (devoid of RNA) viruslike particles (eVLPs) of Cowpea mosaic virus can now be obtained readily. CPMV can encapsulate, within the protein capsid, cobalt or iron oxide by environmentally benign processes. The external surface also remains amenable to chemical modification. The development of eVLPs for targeted delivery of therapeutic agents is now a reality.

KW - encapsulation

KW - mineralization

KW - nanoparticles

KW - viruses

U2 - 10.1002/smll.200902135

DO - 10.1002/smll.200902135

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JO - Small

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