Critical review of unstable angina and non-ST elevation myocardial infarction

P. J. Sheridan; D. C. Crossman

doi:10.1136/pmj.78.926.717

Critical review of unstable angina and non-ST elevation myocardial infarction

P. J. Sheridan, D. C. Crossman

Research output: Contribution to journal › Article

20 Citations (Scopus)

Abstract

Within the coronary vasculature the progression of a stable atherosclerotic plaque into a vulnerable and ultimately unstable lesion leads to a cascade of events culminating in the clinical presentation of unstable angina or acute myocardial infarction. In recent years studies have provided new insights in to the pathology and natural history, stimulating advances in diagnosis, treatment, and management. The review discusses the progress made including the role of inflammation, cardiac biomarkers, antiplatelet therapy, and percutaneous intervention. Current issues of debate and future directions are also addressed.

Original language	English
Pages (from-to)	717-726
Number of pages	10
Journal	Postgraduate Medical Journal
Volume	78
Issue number	926
DOIs	https://doi.org/10.1136/pmj.78.926.717
Publication status	Published - 2002

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10.1136/pmj.78.926.717

Cite this

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AB - Within the coronary vasculature the progression of a stable atherosclerotic plaque into a vulnerable and ultimately unstable lesion leads to a cascade of events culminating in the clinical presentation of unstable angina or acute myocardial infarction. In recent years studies have provided new insights in to the pathology and natural history, stimulating advances in diagnosis, treatment, and management. The review discusses the progress made including the role of inflammation, cardiac biomarkers, antiplatelet therapy, and percutaneous intervention. Current issues of debate and future directions are also addressed.

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