Abstract
In the context of discovering and quantifying terminal alkyne-based natural products, here we report the combination of CuAAC click chemistry with LC-MS for the detection of polyether toxins (prymnesins) associated with harmful algal blooms. The added-value of the CuAAC-based approach is evident from our ability to detect novel prymnesin-like compounds in algal species with previously uncharacterised toxins.
Original language | English |
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Pages (from-to) | 12234-12237 |
Journal | Chemical Communications |
Volume | 54 |
Issue number | 86 |
Early online date | 12 Oct 2018 |
DOIs | |
Publication status | Published - 7 Nov 2018 |