Projects per year
Objectives: According to clinical and comissioning guidelines for chronic rhinosinusitis (CRS), patients being referred to secondary care should have failed primary medical treatment with nasal douching (ND) and intranasal corticosteroids (INCS). The study objectives were to identify the rate of specific medical therapy in CRS patients and establish any differences in medication use, for both CRS and associated medical conditions, between CRS phenotypes.
Design and setting: Case-control study in a secondary care setting.
Methods: Participant-reported study-specific questionnaire capturing free text data on current medication use at the time of study entry. Qualitative interviews with 21 participants also explored their experience of CRS and its management.
Particpants: Patients with both without (CRSsNPs) and with polyps (CRSwNPs). Main outcome measuresReported use of CRS-related and non-related medications.ResultsWithin a total of 1243 CRS participants, current INCS usage was low (18% in CRSwNPs, 12% in CRSsNPs); ND was being performed by only 1% of all participants. Bronchodilators and inhaled corticosteroids use was significantly higher in CRSwNPs participants (p < 0.0001). Antidepressants use was significantly higher in CRSsNPs (14% versus 7%, p < 0.0002). There were no significant regional variations in rates of INCS use, nor any significant influence of social deprivation.
Conclusions: The current use of baseline medical therapy in CRS appears to be very low, representing a combination of poor patient compliance, possible ineffectiveness of treatment and a lack of familiarity with current guidelines amongst general practitioners and some ENT specialists. Work is needed to disseminate guidelines to all practitioners involved and reduce unnecessary burden on existing healthcare resources for this common condition by ensuring timely referral and definitive management.
|Number of pages||16|
|Early online date||11 Dec 2017|
|Publication status||Published - Apr 2018|
- Intranasal Administration
- Patient Compliance
- Therapeutic Irrigation
- 1 Finished
Clinical Senior Lectureship - Clinical Research Ear, Nose and Throat
Fraser, W., Harvey, I. & Philpott, C.
James Paget University Hospitals NHS Foundation Trust
1/01/10 → 31/03/20
- 15 Citations (Scopus)
- 6 Article
Evaluation of smoking as a modifying factor in chronic rhinosinusitisHutson, K., Clark, A., Hopkins, C., Ahmed, S., Kumar, N., Carrie, S., Erskine, S., Sunkaraneni, V., Philpott, C. & CRES group, Feb 2021, In: JAMA Otolaryngology. 147, 2, p. 159-165 7 p.
Research output: Contribution to journal › Article › peer-reviewOpen AccessFile9 Citations (Scopus)1 Downloads (Pure)
Exploring the association between ingestion of foods with higher potential salicylate content and symptom exacerbation in chronic rhinosinusitis: Data from the National Chronic Rhinosinusitis Epidemiology StudyPhilpott, C., Smith, R., Davies-Husband, C., Erskine, S., Clark, A., Welch, A., Hopkins, C., Carrie, S., Ray, J., Sunkaraneni, V., Kara, N., Kumar, N., Robertson, A., Anari, S., Almeyda, R., Wilson, A. & CRES group, Jun 2019, In: Rhinology. 57, 4, p. 303-312 10 p.
Research output: Contribution to journal › Article › peer-reviewOpen AccessFile7 Citations (Scopus)15 Downloads (Pure)
Eustachian tube symptoms are frequent in chronic rhinosinusitis and respond well to endoscopic sinus surgeryManiakas, A., Desrosiers, M., Asmar, M-H., Al Falasi, M., Mfuna Endam, L., Hopkins, C., Philpott, C., Erskine, S., Smith, R. & Kilty, S., Aug 2018, In: Rhinology. 56, 2, p. 118-121 4 p.
Research output: Contribution to journal › Article › peer-reviewOpen AccessFile12 Citations (Scopus)15 Downloads (Pure)