Decomplexation-nitroso Diels-Alder (NDA) approach to C,D-ring functionalisation for hippeastrine

G. Richard Stephenson; Andrew M. Balfe; David L. Hughes; Richard D. Kelsey

doi:10.1016/j.tetlet.2010.09.118

Decomplexation-nitroso Diels-Alder (NDA) approach to C,D-ring functionalisation for hippeastrine

G. Richard Stephenson, Andrew M. Balfe, David L. Hughes, Richard D. Kelsey

Chemistry of Materials and Catalysis

Research output: Contribution to journal › Article › peer-review

16 Citations (Scopus)

Abstract

A tandem decomplexation-nitroso Diels-Alder (decomplexation-NDA) procedure has been shown to give the regiocontrol and stereocontrol needed for application in an organoiron-mediated synthesis of the alkaloid hippeastrine, using a selection of nitrosoarenes with functionality present to facilitate removal of the arene after the NDA step. (C) 2010 Elsevier Ltd. All rights reserved.

Original language	English
Pages (from-to)	6806-6809
Number of pages	4
Journal	Tetrahedron Letters
Volume	51
Issue number	52
DOIs	https://doi.org/10.1016/j.tetlet.2010.09.118
Publication status	Published - 2010

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10.1016/j.tetlet.2010.09.118

Cite this

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title = "Decomplexation-nitroso Diels-Alder (NDA) approach to C,D-ring functionalisation for hippeastrine",

abstract = "A tandem decomplexation-nitroso Diels-Alder (decomplexation-NDA) procedure has been shown to give the regiocontrol and stereocontrol needed for application in an organoiron-mediated synthesis of the alkaloid hippeastrine, using a selection of nitrosoarenes with functionality present to facilitate removal of the arene after the NDA step. (C) 2010 Elsevier Ltd. All rights reserved.",

author = "Stephenson, {G. Richard} and Balfe, {Andrew M.} and Hughes, {David L.} and Kelsey, {Richard D.}",

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AU - Stephenson, G. Richard

AU - Balfe, Andrew M.

AU - Hughes, David L.

AU - Kelsey, Richard D.

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AB - A tandem decomplexation-nitroso Diels-Alder (decomplexation-NDA) procedure has been shown to give the regiocontrol and stereocontrol needed for application in an organoiron-mediated synthesis of the alkaloid hippeastrine, using a selection of nitrosoarenes with functionality present to facilitate removal of the arene after the NDA step. (C) 2010 Elsevier Ltd. All rights reserved.

U2 - 10.1016/j.tetlet.2010.09.118

DO - 10.1016/j.tetlet.2010.09.118

M3 - Article

VL - 51

SP - 6806

EP - 6809

JO - Tetrahedron Letters

JF - Tetrahedron Letters

SN - 0040-4039

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