Decomplexation-nitroso Diels-Alder (NDA) approach to C,D-ring functionalisation for hippeastrine

G. Richard Stephenson; Andrew M. Balfe; David L. Hughes; Richard D. Kelsey

doi:10.1016/j.tetlet.2010.09.118

Decomplexation-nitroso Diels-Alder (NDA) approach to C,D-ring functionalisation for hippeastrine

G. Richard Stephenson, Andrew M. Balfe, David L. Hughes, Richard D. Kelsey

Chemistry of Materials and Catalysis

Research output: Contribution to journal › Article › peer-review

16 Citations (Scopus)

Abstract

A tandem decomplexation-nitroso Diels-Alder (decomplexation-NDA) procedure has been shown to give the regiocontrol and stereocontrol needed for application in an organoiron-mediated synthesis of the alkaloid hippeastrine, using a selection of nitrosoarenes with functionality present to facilitate removal of the arene after the NDA step. (C) 2010 Elsevier Ltd. All rights reserved.

Original language	English
Pages (from-to)	6806-6809
Number of pages	4
Journal	Tetrahedron Letters
Volume	51
Issue number	52
DOIs	https://doi.org/10.1016/j.tetlet.2010.09.118
Publication status	Published - 2010

Access to Document

10.1016/j.tetlet.2010.09.118

Cite this

@article{9ceb5ec7c1064d1f807546aac24ec859,

title = "Decomplexation-nitroso Diels-Alder (NDA) approach to C,D-ring functionalisation for hippeastrine",

abstract = "A tandem decomplexation-nitroso Diels-Alder (decomplexation-NDA) procedure has been shown to give the regiocontrol and stereocontrol needed for application in an organoiron-mediated synthesis of the alkaloid hippeastrine, using a selection of nitrosoarenes with functionality present to facilitate removal of the arene after the NDA step. (C) 2010 Elsevier Ltd. All rights reserved.",

author = "Stephenson, {G. Richard} and Balfe, {Andrew M.} and Hughes, {David L.} and Kelsey, {Richard D.}",

note = "Stephenson, G. Richard Balfe, Andrew M. Hughes, David L. Kelsey, Richard D.",

year = "2010",

doi = "10.1016/j.tetlet.2010.09.118",

language = "English",

volume = "51",

pages = "6806--6809",

journal = "Tetrahedron Letters",

issn = "0040-4039",

publisher = "Elsevier",

number = "52",

}

TY - JOUR

T1 - Decomplexation-nitroso Diels-Alder (NDA) approach to C,D-ring functionalisation for hippeastrine

AU - Stephenson, G. Richard

AU - Balfe, Andrew M.

AU - Hughes, David L.

AU - Kelsey, Richard D.

N1 - Stephenson, G. Richard Balfe, Andrew M. Hughes, David L. Kelsey, Richard D.

PY - 2010

Y1 - 2010

N2 - A tandem decomplexation-nitroso Diels-Alder (decomplexation-NDA) procedure has been shown to give the regiocontrol and stereocontrol needed for application in an organoiron-mediated synthesis of the alkaloid hippeastrine, using a selection of nitrosoarenes with functionality present to facilitate removal of the arene after the NDA step. (C) 2010 Elsevier Ltd. All rights reserved.

AB - A tandem decomplexation-nitroso Diels-Alder (decomplexation-NDA) procedure has been shown to give the regiocontrol and stereocontrol needed for application in an organoiron-mediated synthesis of the alkaloid hippeastrine, using a selection of nitrosoarenes with functionality present to facilitate removal of the arene after the NDA step. (C) 2010 Elsevier Ltd. All rights reserved.

U2 - 10.1016/j.tetlet.2010.09.118

DO - 10.1016/j.tetlet.2010.09.118

M3 - Article

SN - 0040-4039

VL - 51

SP - 6806

EP - 6809

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 52

ER -