Defects in the origin licensing checkpoint stresses cells exiting G0

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The full licensing of replication origins in late G1 is normally enforced by the licensing checkpoint. In this issue, Matson et al. (2019. J. Cell Biol. show that this checkpoint is inoperative in cells exiting from G0, resulting in incomplete origin licensing and consequent replicative stress.
Original languageEnglish
Pages (from-to)2080-2081
Number of pages2
JournalJournal of Cell Biology
Issue number7
Early online date11 Jun 2019
Publication statusPublished - 1 Jul 2019

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