Denosumab for treatment of bone metastases secondary to solid tumours: systematic review and network meta-analysis

John A Ford, Rob Jones, Andrew Elders, Clive Mulatero, Pamela Royle, Pawana Sharma, Fiona Stewart, Radha Todd, Graham Mowatt

Research output: Contribution to journalArticle

39 Citations (Scopus)

Abstract

To evaluate the evidence for denosumab for the treatment of bone metastases secondary to solid tumours and, using a network meta-analysis, indirectly compare denosumab with bisphosphonates and best supportive care.
Original languageEnglish
Pages (from-to)416-30
Number of pages15
JournalEuropean Journal of Cancer
Volume49
Issue number2
DOIs
Publication statusPublished - Jan 2013

Keywords

  • Antibodies, Monoclonal, Humanized
  • Antineoplastic Agents
  • Antineoplastic Combined Chemotherapy Protocols
  • Bone Neoplasms
  • Humans
  • Neoplasms
  • Survival Analysis

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