Denosumab for treatment of bone metastases secondary to solid tumours: systematic review and network meta-analysis

John A Ford; Rob Jones; Andrew Elders; Clive Mulatero; Pamela Royle; Pawana Sharma; Fiona Stewart; Radha Todd; Graham Mowatt

doi:10.1016/j.ejca.2012.07.016

Denosumab for treatment of bone metastases secondary to solid tumours: systematic review and network meta-analysis

John A Ford, Rob Jones, Andrew Elders, Clive Mulatero, Pamela Royle, Pawana Sharma, Fiona Stewart, Radha Todd, Graham Mowatt

Research output: Contribution to journal › Article › peer-review

55 Citations (Scopus)

Abstract

To evaluate the evidence for denosumab for the treatment of bone metastases secondary to solid tumours and, using a network meta-analysis, indirectly compare denosumab with bisphosphonates and best supportive care.

Original language	English
Pages (from-to)	416-30
Number of pages	15
Journal	European Journal of Cancer
Volume	49
Issue number	2
DOIs	https://doi.org/10.1016/j.ejca.2012.07.016
Publication status	Published - Jan 2013

Keywords

Antibodies, Monoclonal, Humanized
Antineoplastic Agents
Antineoplastic Combined Chemotherapy Protocols
Bone Neoplasms
Humans
Neoplasms
Survival Analysis

Access to Document

10.1016/j.ejca.2012.07.016

Cite this

@article{478b2eeca27449959f8c7b22cabf2121,

title = "Denosumab for treatment of bone metastases secondary to solid tumours: systematic review and network meta-analysis",

abstract = "To evaluate the evidence for denosumab for the treatment of bone metastases secondary to solid tumours and, using a network meta-analysis, indirectly compare denosumab with bisphosphonates and best supportive care.",

keywords = "Antibodies, Monoclonal, Humanized, Antineoplastic Agents, Antineoplastic Combined Chemotherapy Protocols, Bone Neoplasms, Humans, Neoplasms, Survival Analysis",

author = "Ford, {John A} and Rob Jones and Andrew Elders and Clive Mulatero and Pamela Royle and Pawana Sharma and Fiona Stewart and Radha Todd and Graham Mowatt",

year = "2013",

month = jan,

doi = "10.1016/j.ejca.2012.07.016",

language = "English",

volume = "49",

pages = "416--30",

journal = "European Journal of Cancer",

issn = "1879-0852",

publisher = "Elsevier",

number = "2",

}

TY - JOUR

T1 - Denosumab for treatment of bone metastases secondary to solid tumours

T2 - systematic review and network meta-analysis

AU - Ford, John A

AU - Jones, Rob

AU - Elders, Andrew

AU - Mulatero, Clive

AU - Royle, Pamela

AU - Sharma, Pawana

AU - Stewart, Fiona

AU - Todd, Radha

AU - Mowatt, Graham

PY - 2013/1

Y1 - 2013/1

N2 - To evaluate the evidence for denosumab for the treatment of bone metastases secondary to solid tumours and, using a network meta-analysis, indirectly compare denosumab with bisphosphonates and best supportive care.

AB - To evaluate the evidence for denosumab for the treatment of bone metastases secondary to solid tumours and, using a network meta-analysis, indirectly compare denosumab with bisphosphonates and best supportive care.

KW - Antibodies, Monoclonal, Humanized

KW - Antineoplastic Agents

KW - Antineoplastic Combined Chemotherapy Protocols

KW - Bone Neoplasms

KW - Humans

KW - Neoplasms

KW - Survival Analysis

U2 - 10.1016/j.ejca.2012.07.016

DO - 10.1016/j.ejca.2012.07.016

M3 - Article

C2 - 22906748

SN - 1879-0852

VL - 49

SP - 416

EP - 430

JO - European Journal of Cancer

JF - European Journal of Cancer

IS - 2

ER -