Depsipeptides and their Therapeutic Use

Graham Packham (Inventor), A. Ganesan (Inventor), Alexander Richard Liam Cecil (Inventor)

Research output: Patent


Compounds which are Spiruchostatin analogues of the general formula (I) or (I'), isosteres thereof and pharmaceutically acceptable salts thereof are found to inhibit HDAC wherein R1, R2, R3 and R4 are the same or different and represent an amino acid side chain moiety and each R6 is the same or different and represents hydrogen or C1-C4 alkyl.
Original languageEnglish
Patent numberWO2008062232
Publication statusPublished - 2008

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