Depsipeptides and their Therapeutic Use

Graham Packham; A. Ganesan; Alexander Richard Liam Cecil

Depsipeptides and their Therapeutic Use

Graham Packham (Inventor), A. Ganesan (Inventor), Alexander Richard Liam Cecil (Inventor)

Research output: Patent

Abstract

Compounds which are Spiruchostatin analogues of the general formula (I) or (I'), isosteres thereof and pharmaceutically acceptable salts thereof are found to inhibit HDAC wherein R1, R2, R3 and R4 are the same or different and represent an amino acid side chain moiety and each R6 is the same or different and represents hydrogen or C1-C4 alkyl.

Original language	English
Patent number	WO2008062232
Publication status	Published - 2008

Cite this

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title = "Depsipeptides and their Therapeutic Use",

abstract = "Compounds which are Spiruchostatin analogues of the general formula (I) or (I'), isosteres thereof and pharmaceutically acceptable salts thereof are found to inhibit HDAC wherein R1, R2, R3 and R4 are the same or different and represent an amino acid side chain moiety and each R6 is the same or different and represents hydrogen or C1-C4 alkyl.",

author = "Graham Packham and A. Ganesan and Cecil, {Alexander Richard Liam}",

year = "2008",

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AU - Ganesan, A.

AU - Cecil, Alexander Richard Liam

PY - 2008

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N2 - Compounds which are Spiruchostatin analogues of the general formula (I) or (I'), isosteres thereof and pharmaceutically acceptable salts thereof are found to inhibit HDAC wherein R1, R2, R3 and R4 are the same or different and represent an amino acid side chain moiety and each R6 is the same or different and represents hydrogen or C1-C4 alkyl.

AB - Compounds which are Spiruchostatin analogues of the general formula (I) or (I'), isosteres thereof and pharmaceutically acceptable salts thereof are found to inhibit HDAC wherein R1, R2, R3 and R4 are the same or different and represent an amino acid side chain moiety and each R6 is the same or different and represents hydrogen or C1-C4 alkyl.

M3 - Patent

M1 - WO2008062232

ER -