Detecting Analytes

Andy Mount; Mizanur Khondoker; Ilenia Ciani; Till Bachmann; Peter Ghazal

Detecting Analytes

Andy Mount, Mizanur Khondoker, Ilenia Ciani, Till Bachmann, Peter Ghazal

Research output: Other contribution

Abstract

The application is directed to the impedimetric determination of analyte binding, eg. DNA hybridisation using electrochemical impedance spectrometry (EIS). In one embodiment, simultaneous multi-frequency excitation is used, followed by FFT. In another, a differential method is used to monitor the rate of change of EIS variables, especially the electron transfer resistance, Ret. Combining EIS with labels allows the multiplex determination of a plurality of analytes. Also, kinetic monitoring of enzyme activity, especially of protease in wound healing, becomes possible.

Original language	English
Type	Patent
Publication status	Published - 1 Jun 2011

Access to Document

https://patentscope.wipo.int/search/en/detail.jsf?docId=WO2011069997

Cite this

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title = "Detecting Analytes",

abstract = "The application is directed to the impedimetric determination of analyte binding, eg. DNA hybridisation using electrochemical impedance spectrometry (EIS). In one embodiment, simultaneous multi-frequency excitation is used, followed by FFT. In another, a differential method is used to monitor the rate of change of EIS variables, especially the electron transfer resistance, Ret. Combining EIS with labels allows the multiplex determination of a plurality of analytes. Also, kinetic monitoring of enzyme activity, especially of protease in wound healing, becomes possible.",

author = "Andy Mount and Mizanur Khondoker and Ilenia Ciani and Till Bachmann and Peter Ghazal",

year = "2011",

month = jun,

day = "1",

language = "English",

type = "Other",

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TY - GEN

T1 - Detecting Analytes

AU - Mount, Andy

AU - Khondoker, Mizanur

AU - Ciani, Ilenia

AU - Bachmann, Till

AU - Ghazal, Peter

PY - 2011/6/1

Y1 - 2011/6/1

N2 - The application is directed to the impedimetric determination of analyte binding, eg. DNA hybridisation using electrochemical impedance spectrometry (EIS). In one embodiment, simultaneous multi-frequency excitation is used, followed by FFT. In another, a differential method is used to monitor the rate of change of EIS variables, especially the electron transfer resistance, Ret. Combining EIS with labels allows the multiplex determination of a plurality of analytes. Also, kinetic monitoring of enzyme activity, especially of protease in wound healing, becomes possible.

AB - The application is directed to the impedimetric determination of analyte binding, eg. DNA hybridisation using electrochemical impedance spectrometry (EIS). In one embodiment, simultaneous multi-frequency excitation is used, followed by FFT. In another, a differential method is used to monitor the rate of change of EIS variables, especially the electron transfer resistance, Ret. Combining EIS with labels allows the multiplex determination of a plurality of analytes. Also, kinetic monitoring of enzyme activity, especially of protease in wound healing, becomes possible.

M3 - Other contribution

ER -