Detecting Analytes

Andy Mount, Mizanur Khondoker, Ilenia Ciani, Till Bachmann, Peter Ghazal

Research output: Other contribution


The application is directed to the impedimetric determination of analyte binding, eg. DNA hybridisation using electrochemical impedance spectrometry (EIS). In one embodiment, simultaneous multi-frequency excitation is used, followed by FFT. In another, a differential method is used to monitor the rate of change of EIS variables, especially the electron transfer resistance, Ret. Combining EIS with labels allows the multiplex determination of a plurality of analytes. Also, kinetic monitoring of enzyme activity, especially of protease in wound healing, becomes possible.
Original languageEnglish
Publication statusPublished - 1 Jun 2011

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