Determinants of exercise capacity in patients with coronary artery disease and mild to moderate systolic dysfunction. Role of heart rate and diastolic filling abnormalities

S S Lele, D Macfarlane, S Morrison, H Thomson, F Khafagi, M Frenneaux

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28 Citations (Scopus)


To test the hypothesis that diastolic filling abnormalities are an important cause of exercise limitation in some patients with coronary artery disease we assessed the factors limiting exercise capacity in a group of patients with coronary artery disease in whom exercise limitation was greater than expected from the degree of resting left ventricular systolic dysfunction.
Original languageEnglish
Pages (from-to)204-212
Number of pages9
JournalEuropean Heart Journal
Issue number2
Publication statusPublished - Feb 1996


  • Adult
  • Aged
  • Blood Pressure
  • Cardiac Output
  • Coronary Disease
  • Diastole
  • Exercise Test
  • Female
  • Hemodynamics
  • Humans
  • Male
  • Middle Aged
  • Multivariate Analysis
  • Oxygen Consumption
  • Radionuclide Ventriculography
  • Stroke Volume
  • Systole
  • Time Factors
  • Ventricular Dysfunction, Left

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