Determination of Molecular Torsion Angles Using Nuclear Singlet Relaxation

Michael C. D. Tayler, Sabrina Marie, A. Ganesan, Malcolm H. Levitt

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39 Citations (Scopus)

Abstract

The exponential relaxation time constant, TS, of a nuclear singlet state is influenced by the proximity of neighboring NMR-active nuclei. For methylene groups in particular this dependence is much stronger than the case for other NMR relaxation constants, including the “conventional” relaxation time constant, T1, of the longitudinal magnetization. This sensitivity provides a new route for determining torsional angles plus other molecular structural details in the isotropic solution phase.
Original languageEnglish
Pages (from-to)8225-8227
Number of pages3
JournalJournal of the American Chemical Society
Volume132
Issue number24
DOIs
Publication statusPublished - 27 May 2010

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