Development, implementation and cost-effectiveness of a protocol for review of combination diuretic prescribing

Julie D. Morgan; David J. Wright; Henry Chrystyn; Bethan George; Andrew C. Booth; David J. Shoesmith

doi:10.1046/j.1365-2125.2003.01784.x

Development, implementation and cost-effectiveness of a protocol for review of combination diuretic prescribing

Julie D. Morgan, David J. Wright, Henry Chrystyn, Bethan George, Andrew C. Booth, David J. Shoesmith

Patient Care

Research output: Contribution to journal › Article › peer-review

2 Citations (Scopus)

Abstract

Aims To determine the extent of inappropriate prescribing of combination diuretics and the cost implications of protocol implementation. Methods Pharmacist-run medication review clinics in two general practices in Bradford, UK. Results Sixty-one patients, mean ± s.d. age 75.8 ± 12.0 years, were reviewed. Thirty-six met protocol criteria; 30 (49.2%) patients had their potassium-sparing diuretics (PSDs) discontinued. Mean (95% confidence interval) reduction in serum potassium concentrations after intervention in these 30 patients was 0.26 (0.09, 0.43) mmol l-1 (P < 0.01). Twenty-eight (93.3%) patients were within the reference range at follow-up; none was below. Conclusions Of prescribed PSDs, 59% were found to be unnecessary. Using the developed protocol potentially improves drug safety and enables cost savings.

Original language	English
Pages (from-to)	317-320
Number of pages	4
Journal	British Journal of Clinical Pharmacology
Volume	55
Issue number	3
DOIs	https://doi.org/10.1046/j.1365-2125.2003.01784.x
Publication status	Published - 2003

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10.1046/j.1365-2125.2003.01784.x

Cite this

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title = "Development, implementation and cost-effectiveness of a protocol for review of combination diuretic prescribing",

abstract = "Aims To determine the extent of inappropriate prescribing of combination diuretics and the cost implications of protocol implementation. Methods Pharmacist-run medication review clinics in two general practices in Bradford, UK. Results Sixty-one patients, mean ± s.d. age 75.8 ± 12.0 years, were reviewed. Thirty-six met protocol criteria; 30 (49.2%) patients had their potassium-sparing diuretics (PSDs) discontinued. Mean (95% confidence interval) reduction in serum potassium concentrations after intervention in these 30 patients was 0.26 (0.09, 0.43) mmol l-1 (P < 0.01). Twenty-eight (93.3%) patients were within the reference range at follow-up; none was below. Conclusions Of prescribed PSDs, 59% were found to be unnecessary. Using the developed protocol potentially improves drug safety and enables cost savings.",

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T1 - Development, implementation and cost-effectiveness of a protocol for review of combination diuretic prescribing

AU - Morgan, Julie D.

AU - Wright, David J.

AU - Chrystyn, Henry

AU - George, Bethan

AU - Booth, Andrew C.

AU - Shoesmith, David J.

PY - 2003

Y1 - 2003

N2 - Aims To determine the extent of inappropriate prescribing of combination diuretics and the cost implications of protocol implementation. Methods Pharmacist-run medication review clinics in two general practices in Bradford, UK. Results Sixty-one patients, mean ± s.d. age 75.8 ± 12.0 years, were reviewed. Thirty-six met protocol criteria; 30 (49.2%) patients had their potassium-sparing diuretics (PSDs) discontinued. Mean (95% confidence interval) reduction in serum potassium concentrations after intervention in these 30 patients was 0.26 (0.09, 0.43) mmol l-1 (P < 0.01). Twenty-eight (93.3%) patients were within the reference range at follow-up; none was below. Conclusions Of prescribed PSDs, 59% were found to be unnecessary. Using the developed protocol potentially improves drug safety and enables cost savings.

AB - Aims To determine the extent of inappropriate prescribing of combination diuretics and the cost implications of protocol implementation. Methods Pharmacist-run medication review clinics in two general practices in Bradford, UK. Results Sixty-one patients, mean ± s.d. age 75.8 ± 12.0 years, were reviewed. Thirty-six met protocol criteria; 30 (49.2%) patients had their potassium-sparing diuretics (PSDs) discontinued. Mean (95% confidence interval) reduction in serum potassium concentrations after intervention in these 30 patients was 0.26 (0.09, 0.43) mmol l-1 (P < 0.01). Twenty-eight (93.3%) patients were within the reference range at follow-up; none was below. Conclusions Of prescribed PSDs, 59% were found to be unnecessary. Using the developed protocol potentially improves drug safety and enables cost savings.

U2 - 10.1046/j.1365-2125.2003.01784.x

DO - 10.1046/j.1365-2125.2003.01784.x

M3 - Article

VL - 55

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EP - 320

JO - British Journal of Clinical Pharmacology

JF - British Journal of Clinical Pharmacology

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