Diagnostic utility of testing for antineutrophil cytoplasmic antibodies

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Antineutrophil cytoplasmic antibodies (ANCA) that target the third neutral serine proteinase (PR3) and myeloperoxidase (MPO) of human neutrophils are associated with primary systemic vasculitis that predominantly affects small and medium blood vessels.1,2 There is an international consensus that testing for ANCA should specifically be focused on identifying antibodies against those 2 antigenic targets.3 In this edition of the journal, Wójcik et al4 discuss the data from the Polish Vasculitis Register (POLVAS) including information from 536 individuals who presented with vasculitis over 27 years, in the demographic context.
Original languageEnglish
Article number16224
JournalPolskie Archiwum Medycyny Wewnetrznej
Issue number3
Publication statusPublished - 30 Mar 2022

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