Direct transcriptional control of the Arabidopsis immune receptor FLS2 by the ethylene-dependent transcription factors EIN3 and EIL1

Freddy Boutrot, Cécile Segonzac, Katherine N. Chang, Hong Qiao, Joseph R. Ecker, Cyril Zipfel, John P. Rathjen

Research output: Contribution to journalArticle

153 Citations (Scopus)

Abstract

In plant innate immunity, the leucine-rich repeat receptor kinase FLS2 recognizes the bacterial pathogen-associated molecular pattern (PAMP) flagellin. The molecular mechanisms underlying PAMP perception are not fully understood. Here, we reveal that the gaseous phytohormone ethylene is an integral part of PAMP-triggered immunity. Plants mutated in the key ethylene-signaling protein EIN2 are impaired in all FLS2-mediated responses, correlating with reduced FLS2 transcription and protein accumulation. The EIN3 and EIN3-like transcription factors, which depend on EIN2 activity for their accumulation, directly control FLS2 expression. Our results reveal a direct role for ethylene in regulation of an innate immune receptor.
Original languageEnglish
Pages (from-to)14502-14507
Number of pages6
JournalProceedings of the National Academy of Sciences of the United States of America (PNAS)
Volume107
Issue number32
DOIs
Publication statusPublished - 10 Aug 2010

Keywords

  • Arabidopsis
  • Arabidopsis Proteins
  • Ethylenes
  • Gene Expression Regulation, Plant
  • Immunity, Innate
  • Nuclear Proteins
  • Protein Kinases
  • Receptors, Immunologic
  • Transcription Factors

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